feedback inhibition


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Related to feedback inhibition: Allosteric regulation

feedback inhibition

n.
A cellular control mechanism in which an enzyme that catalyzes the production of a particular substance in the cell is inhibited when that substance has accumulated to a certain level, thereby balancing the amount provided with the amount needed.
References in periodicals archive ?
Rao and Ravishankar [13] reported that it was possible that the by-products in the spent medium could lead to unwanted feedback inhibition towards the products of interest.
Some evidence suggests that glucocorticoids play a role in hippocampal inhibition of anticipatory responses, as lesions can block feedback inhibition of the HPA axis by the synthetic steroid dexamethasone (Magarinos et al.
Along with its numerous actions in the body, cortisol has feedback inhibition on the PVN and the anterior pituitary to control CRH or synthesis and release of ACTH.
Common single-nucleotide polymorphisms in genes regulating the feedback inhibition of bile acid synthesis, specifically the FGF19-mediated feedback pathway, affect chenodeoxycholate-mediated acceleration of colonic transit in IBS-C [constipation-predominant irritable bowel syndrome], and perhaps less so in health," Dr.