feedback inhibition


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Related to feedback inhibition: Allosteric regulation

feedback inhibition

n.
A cellular control mechanism in which an enzyme that catalyzes the production of a particular substance in the cell is inhibited when that substance has accumulated to a certain level, thereby balancing the amount provided with the amount needed.
References in periodicals archive ?
As the folate biosynthetic enzymes are not present in the vacuole, it may be possible to accumulate folate without feedback inhibition of its synthesis by directing folate import into this organelle.
Endocrine systems with feedback inhibition are considered as well as protein binding, binding kinetics, and the laboratory measurement of bioactive fractions of protein-bound constituents.
Studies indicated that lysine decarboxylase might be subject to an end-product feedback inhibition mechanism in vivo (Pelosi et al.
Thus calmodulin can act as a key molecule both in stimulation of gene transcription and other cellular events and in feedback inhibition of calcium channels.