Her normal diet and exercise routine wasn't working, so Mary went to her doctor and received a prescription for a popular combination weight loss drug, Fen-Phen
, which she took for just 23 days.
(37) The high rate of deficiency, of course, was explained by the screening process: entire industries had been spawned to screen potential fen-phen
claimants; screening sessions were being held in law firms and hotel rooms; diagnosing physicians were working on contingency fees with escalating rewards for more serious diagnoses; (38) and some diagnosing physicians were finding injuries at twelve times the rate predicted by their own research studies.
However, secrecy was upended during the fen-phen
In 1997, clinicians in Fargo, North Dakota, and the Mayo Clinic notified Wyeth that they had seen thirteen patients on Fen-Phen
who had developed valvular disease.
Alida Mundy, author of Dispensing With the Truth, a book about the battle over Fen-Phen
, is a senior editor at Cableworld.
In Trenton, New Jersey, jury selection began this week in a test case involving thousands of healthy fen-phen
As for "magic pills" that melt the body fat away, we've learned the hard way that such drugs as Redux and fen-phen
, as well as over-the-counter weight control products with ephedrine and caffeine, are themselves hazardous.
THE DIET drug known as Fen-Phen
was recently implicated as a cause of valvular heart disease in women.
A highly publicized and well-documented example of the association between off-label drug use and the potential for adverse effects was observed with the drug fenfluramine/ phentermine (fen-phen
Side effects may include symptoms such as nausea, vomiting and diarrhea, but may be as severe as valvular heart disease, as in the case of the now-banned weight loss drug Fen-Phen
. Many of these drugs are new, though, so long-term side effects have not yet been reported.
After the fen-phen
debacle, we should be wary of any diet pill.
The year after chairing the panel, Pi-Sunyer was identified in a lawsuit as the guest author of a ghostwritten review on obesity commissioned by Wyeth-Ayerst regarding long-term, off-label use of the dangerous "fen-phen
" combination (fenfluramine and phentermine).