fenfluramine hydrochloride

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fen·flu·ra·mine hydrochloride

A drug that suppresses appetite by altering brain levels of serotonin, formerly used in the management of obesity.

[Shortening and rearrangement of (tri)flu(o)r(omethyl)phen(ethyl)amine, one of its constituents.]
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Fenfluramine trials for patients with a rare, devastating form of epilepsy was also introduced and Cook Children's celebrated its 10th year anniversary of Deep Stimulation Surgery (DBS) for pediatric patients.
Although still available in many countries, phentermine and diethylpropion were largely superseded by the serotonin (5-HT)-releasing agents fenfluramine and dexfenfluramine.
As part of the deal, Zogenix acquires global development and commercialisation rights to the low-dose fenfluramine Brabafen for the treatment of Dravet syndrome, a form of intractable epilepsy that begins in infancy.
Other serotonergic medications previously used for weight loss, such as fenfluramine, stimulated the serotonin 2b receptor, which may have contributed to an increased risk of cardiac valve disease.
Neither of these recalls, however, can compare with the $21 billion cost of Wyeth's fenfluramine recall in 1997 (12).
One of them--Fen-Phen, a combination of phentermine and fenfluramine--was linked to heart-valve disorders, but those problems were attributed only to the pill's fenfluramine component.
In the 19905, medical researchers gave a banned diet drug, fenfluramine, to dozens of African-American and Hispanic boys, aged 6 to so, to see, bizarrely, whether or not the drug could help predict if the boys were likely to become criminals as adults.
Cardiac valvulopathy associated with exposure to fenfluramine or dexfenfluramine: U.
Recall that fenfluramine (the "fen" in "fen-phen") was a serotonergic agent that caused cardiac valvulopathy and was withdrawn from the market.
Rich's medical license being placed on two years probation with specified conditions because he failed to maintain the advocacy of another doctor and the Tennessee Medical (Foundation), in accordance with the conditions of his licensure, and because he instructed his eighteen-year-old receptionist to fill out presigned prescriptions for Phentermine and Fenfluramine for patients while he was on vacation.
Among the illegally marketed products are those containing drugs that have been withdrawn from the market for safety reasons, including the weight-loss drugs sibutramine and fenfluramine.
The section of the brain affected by the drug is part of the same complex of receptors targeted by fenfluramine, an ingredient in Wyeth's fen-phen drug combination that was pulled from the U.