fenfluramine hydrochloride


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fen·flu·ra·mine hydrochloride

 (fĕn-flo͝or′ə-mēn′)
n.
A drug that suppresses appetite by altering brain levels of serotonin, formerly used in the management of obesity.

[Shortening and rearrangement of (tri)flu(o)r(omethyl)phen(ethyl)amine, one of its constituents.]
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Zogenix Inc (NASDAQ: ZGNX) has recorded positive top-line results in the second confirmatory Phase 3 trial of its investigational drug, ZX008 (low-dose fenfluramine hydrochloride), in children and young adults with Dravet syndrome, the company revealed on Thursday.
Fenfluramine hydrochloride is a Class IV controlled substance and is classified by the Physician's Desk Reference as an anorectic.
Much recent work has documented the safety and efficacy of appetite suppressants in weight control.[7-46] Appetite suppressants that have been studied and found to be safe, effective, and of low abuse potential include diethylpropion hydrochloride (75 mg daily), mazindol (1 mg daily), phentermine hydrochloride, fenfluramine hydrochloride (d-fenfluramine and the racemic dl-fenfluramine), fluoxetine hydrochloride (60 to 80 mg daily), and phenylpropanolamine hydrochloride (75 mg daily, available over the counter)[7-46] (Table).