Decreased mean platelet volume is associated with the developing stage of fetoplacental unit
in spontaneous abortion.
As a result of impaired uteroplacental blood flow, manifestations of preeclampsia may be seen in the fetoplacental unit
like intrauterine growth restriction (IUGR), oligohydramnios, placental abruption and non-reassuring foetal status (NST).
Nearly, all organ systems undergo profound changes during normal pregnancy to meet the demands of the fetoplacental unit
. There are both subtle and substantial changes in hematological parameters during pregnancy and the puerperium, orchestrated by changes in the hormonal milieu.
Given the significant fall in insulin requirement, concerns were raised that this might be due to a failing fetoplacental unit
. Against this, the patient never developed hypertension, and laboratory screening for preeclampsia was performed multiple times and was always within normal limits.
Over the last twenty years Doppler ultrasound has become a reliable and frequently used method to monitor the fetoplacental unit
of risk pregnancies [1-6].
Abnormalities in maternal circulation (maternal vascular malperfusion) can lead to fetoplacental unit
underperfusion and FVM.
Drawing on the results of these animal studies, Offenbacher and his co-investigators developed a series of clinical studies to test the hypothesis that periodontal infections, serving as reservoirs for gram-negative bacteria, might pose a potential threat to the fetoplacental unit
. In 1996, Offenbacheret al conducted a case control study in which they hypothesized that periodontal infections may have some kind of relationship with preterm births.
Recent literature suggests that beyond placental angioarchitecture and transfusion unbalance, other factors such as renin-angiotensin system activation in the fetoplacental unit
are involved in the pathophysiology of this condition (13).
Moreover, adipokines are constitutively expressed by the fetoplacental unit
and are present in cord blood suggesting an involvement of these molecules in fetal development .
Induction of labor (IOL) is the artificial initiation of labor, before its spontaneous onset, for the purpose of delivery of the fetoplacental unit
. The common indications for IOL are post-term pregnancy, premature rupture of membranes, fetal compromise, maternal medical conditions (e.g.
(11) reported regular electrical uterine activity during the third phase of pregnancy that was under the control of estrogens produced by the fetoplacental unit
. Again, the canine placenta lacks steroidogenesis, leaving the eventual uterine motility an unexplained event in dogs.
Glucocorticoids acted on fetoplacental unit
to increase production of estradiol and [PGF.sub.2][alpha] resulting in induced parturition.