They found that when fibrinogen
(a blood-clotting protein) leaks into the central nervous system, it stops brain cells from producing myelin and, as a result, prevents repair.
M2 PHARMA-October 10, 2017-China Biologic passes CFDA approval for commercial manufacturing of human fibrinogen
at facility in Shandong Province, China
Objectives: Congenital dysfibrinogenemia is a rare hereditary disease characterized by normal antigen level but lower function level of fibrinogen
In all patients, C-reactive protein, fibrinogen
, N-terminal of the pro-hormone brain natriuretic peptide and white blood count were measured and transthoracic echocardiography was performed.
Thrombocytopaenia, prolongation of PT or aPTT or both, low fibrinogen
and increased fibrin degradation products are the usual abnormalities.
Recently in the Colombian Journal of Anesthesiology, Garcia Velasquez and collaborators reported the results of an observational study with 79 patients diagnosed with severe PPH in which they found that the concentration of fibrinogen
at the onset of bleeding is associated with severity and morbidity produced by bleeding.
Each component of EVARREST--a Oxidized Regenerated Cellulose (ORC) underlying layer, nonwoven polyglactin 910 fibers needle-punched into the underlying ORC layer to provide increased surface area and mechanical strength and a surface layer of lyophilized human fibrinogen
and human thrombin--plays an active role in the hemostasis process.
USPRwire, Sun Oct 18 2015] Global Markets Direct's, 'Fibrinogen
Deficiency (Factor I Deficiency) - Pipeline Review, H2 2015', provides an overview of the Fibrinogen
Deficiency (Factor I Deficiency)'s therapeutic pipeline.
Our aim was to determine the association between elevated fibrinogen
and decreased high-density lipoprotein cholesterol (HDL-C) levels with recurrent CVT.
ClickPress, Thu Nov 06 2014] GlobalData's clinical trial report, "Fibrinogen
Deficiency (Factor I deficiency) Global Clinical Trials Review, H2, 2014" provides data on the Fibrinogen
Deficiency (Factor I Deficiency) clinical trial scenario.
It is an autosomal recessive disease and occurs as a result of mutation in one of the three genes which code the three polypeptide chains of fibrinogen
Concentrations of fibrinogen
were determined with Chrom 7 coagulometer (Slamed Ing GmbH, Germany), with results displayed as g/l.