The SVD subtype, also called lacuna stroke, usually occurs due to the fibrinoid
necrosis and lipohyalinosis of arterioles affected by hypertension-induced pathological processes.
the severe endothelial dysfunction in malignant arterial hypertension generates fibrinoid
necrosis, myointimal hyperplasia and microangiopathic thrombopathy.
Seven patients died, and postmortem analysis of GI tissues displayed fibrinoid
necrosis of terminal arterioles within the deep mucosa, extravasation of fragmented red blood cells (RBCs) around affected vessels, and extensive crypt depletion in the tip of mucosal folds.
There was no fibrinoid
necrosis, leukocytoclasia or giant cells in the examined biopsy specimen.
Histology of the resected specimen showed fibrous tissue with chronic inflammation and fibrin deposition, and a nodular portion of focally ulcerated squamous mucosa with pseudoepitheliomatous hyperplasia, chronic inflammation, extensive fibrin deposition, and fibrinoid
necrosis of blood vessels.
Placental tissues were available from 4 neonates; common findings were fibrinoid
necrosis, chorangiosis, and amnion hyperplasia.
Necrobiotic granulomas is an another granuloma of unknown etiology in young diabetic people with central fibrinoid
Adherent placenta is characterised by abnormal attachment of placental villi directly to myometrium due to scanty or absence of decidua basalis and imperfect development of fibrinoid
on Nitabuch layer.
necrosis of capillary tufts was seen in three of the glomeruli.
Moreover, in few cases in coronary vessel showed fibrinoid
necrosis represented by circumferential bright pink area of necrosis with protein deposition (Fig.
Results: Heavy placentae with abundant villous immaturity, chorangiosis and syncytial knots in group B and fibrinoid
necrosis and calcification in group C were seen.
Endothelial injury accompanies severe elevations of BP resulting in fibrinoid
necrosis of the arterioles with the deposition of platelets and fibrin, and a breakdown of the normal autoregulatory function.