High scores mean patients have a high risk for hemorrhage if tPA is used thus making them ineligible for the fibrinolytic agent
not available in the EC, and a nurse had to fetch it from the pharmacy (4.
Results announced this weekend at a symposium preceding the 50th Annual Scientific Session of the American College of Cardiology from a study of patients with ST-segment elevation myocardial infarction (commonly referred to as heart attack) showed that the anti-platelet agent INTEGRILIN(R) combined with a half dose of the single-bolus fibrinolytic agent
, TNKase(TM), fully restored blood flow through blocked arteries supplying oxygen-starved heart muscle in 70 percent of patients (n=47) within 60 minutes of initiation of therapy.
In 2006, Biolex plans to enter Phase 1 trials with its BLX-155, a novel, direct acting fibrinolytic agent
CT Poster Session (Abstract #2777/C240): Alfimeprase, a Novel Direct-Acting Fibrinolytic Agent
in Acute Peripheral Arterial Occlusion: Report of a Phase 2, Multi-Center, Open-Label, Dose-Defining Study (NAPA-1) About Nuvelo
The study evaluated the combination of half the standard dose of the clot-dissolving fibrinolytic agent
RETAVASE(R) (reteplase) and a standard dose of ReoPro(R) (abciximab), a drug that prevents the formation of blood clots, as a potential new treatment regimen for heart attack.
Clinical data suggest that Viprinex is a powerful defibrinogenating agent causing enhanced blood flow, a fibrinolytic agent
, as well as an anticoagulant helping to limit stroke extension.
33 (33-74) Men, n (%) 131 (85) Medical history Hypertension, n (%) 55 (35) Diabetes, n (%) 46 (30) Dyslipidemia, n (%) 26(17) Presentation Chest pain, n (%) 147 (95) Anterior location, n (%) 77 (50) Fibrinolytic agent
Streptokinase, n (%) 7 (4.
The patient was then transferred to the intensive care unit, and he was given a fibrinolytic agent
and was started on anti-ischemic therapy.
presented the results of the Clopidogrel as Adjunctive ReperfusIon Therapy-Thrombolysis in Myocardial Infarction trial (CLARITY-TIMI 28), a double-blind study in which 3,491 patients presenting with ST-elevation MI (STEMI) within 12 hours of symptom onset received a fibrinolytic agent
, aspirin, and heparin and were then randomized to oral clopidogrel or placebo.
Retavase[R] (reteplase) is a fibrinolytic agent
that was approved by the U.
In addition, it appears that liposome encapsulation tends to target the drug to the site of the clot, so less fibrinolytic agent