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Related to fibrinolytic agent: thrombolytic agent, fibrinolytic inhibitors


n. pl. fi·bri·nol·y·ses (-sēz′)
The breakdown of fibrin, usually by the enzymatic action of plasmin.

fi′bri·no·lyt′ic (-nə-lĭt′ĭk) adj.


a. fibrinolítico-a, rel. a la desintegración de fibrina.


adj & n fibrinolítico
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High scores mean patients have a high risk for hemorrhage if tPA is used thus making them ineligible for the fibrinolytic agent (Meadows, 2005).
Fibrinolytic agent not available in the EC, and a nurse had to fetch it from the pharmacy (4.
Results announced this weekend at a symposium preceding the 50th Annual Scientific Session of the American College of Cardiology from a study of patients with ST-segment elevation myocardial infarction (commonly referred to as heart attack) showed that the anti-platelet agent INTEGRILIN(R) combined with a half dose of the single-bolus fibrinolytic agent, TNKase(TM), fully restored blood flow through blocked arteries supplying oxygen-starved heart muscle in 70 percent of patients (n=47) within 60 minutes of initiation of therapy.
In 2006, Biolex plans to enter Phase 1 trials with its BLX-155, a novel, direct acting fibrinolytic agent.
CT Poster Session (Abstract #2777/C240): Alfimeprase, a Novel Direct-Acting Fibrinolytic Agent in Acute Peripheral Arterial Occlusion: Report of a Phase 2, Multi-Center, Open-Label, Dose-Defining Study (NAPA-1) About Nuvelo
The study evaluated the combination of half the standard dose of the clot-dissolving fibrinolytic agent RETAVASE(R) (reteplase) and a standard dose of ReoPro(R) (abciximab), a drug that prevents the formation of blood clots, as a potential new treatment regimen for heart attack.
Clinical data suggest that Viprinex is a powerful defibrinogenating agent causing enhanced blood flow, a fibrinolytic agent, as well as an anticoagulant helping to limit stroke extension.
33 (33-74) Men, n (%) 131 (85) Medical history Hypertension, n (%) 55 (35) Diabetes, n (%) 46 (30) Dyslipidemia, n (%) 26(17) Presentation Chest pain, n (%) 147 (95) Anterior location, n (%) 77 (50) Fibrinolytic agent Streptokinase, n (%) 7 (4.
The patient was then transferred to the intensive care unit, and he was given a fibrinolytic agent and was started on anti-ischemic therapy.
presented the results of the Clopidogrel as Adjunctive ReperfusIon Therapy-Thrombolysis in Myocardial Infarction trial (CLARITY-TIMI 28), a double-blind study in which 3,491 patients presenting with ST-elevation MI (STEMI) within 12 hours of symptom onset received a fibrinolytic agent, aspirin, and heparin and were then randomized to oral clopidogrel or placebo.
Retavase[R] (reteplase) is a fibrinolytic agent that was approved by the U.
In addition, it appears that liposome encapsulation tends to target the drug to the site of the clot, so less fibrinolytic agent is needed.