fibrinopeptide


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fibrinopeptide

(ˌfɪbrɪnəʊˈpɛptaɪd)
n
a peptide which combines to form fibrin during blood-clotting
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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Noun1.fibrinopeptide - peptide released from the amino end of fibrinogen by the action of thrombin to form fibrin during clotting of the blood
peptide - amide combining the amino group of one amino acid with the carboxyl group of another; usually obtained by partial hydrolysis of protein
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(13-16) Plasma levels of fibrinopeptide A, a marker of thrombin generation, are increased after attacks of CAS, and there is a circadian variation in the levels in parallel with that of CAS attacks.
Inflammation itself arises from myriad etiologic pathways, with multiple inflammatory mediators potentially involved, including histamines, cytokines, eicosanoids (for example, prostaglandins, thromboxanes, and leukotrienes), complement cascade components, kinins, fibrinopeptide enzymes, nuclear factor-kappa B, and free radicals.
The increased markers of coagulation are thrombin antithrombin complex, tissue factor, and fibrinopeptide B [33].
Homophenotypic Aalpha R16H fibrinogen (Kingsport): uniquely altered polymerization associated with slower fibrinopeptide A than fibrinopeptide B release.
MS/MS analysis of blood plasma of animals intoxicated with RVX revealed fragments of fibrinopeptide A, signifying that exposure to RVX caused inactivation or reduced expression of exopeptidases (aminopeptidases) [192].
Other mechanisms described in the literature include increased activation of Glycoprotein IIb/IIIa, CD41a, CD42b, CD62P and CD6 (3,2,6) prothrombin fragment F1+ 2, thrombin-antithrombin III complex and fibrinopeptide A.
The test evaluates the levels of fibrinopeptide B (FPB), a small peptide that's released when a thrombosis forms and which is removed from the body through urine.
The test assesses the levels of fibrinopeptide B (FPB), a small peptide released when a thrombosis forms and which is cleared from the body through urine.
Fibrin detected in plasma of patients with disseminated intravascular coagulation by fibrin specific antibodies consists primarily of high molecular weight factor XIIIa-crosslinked and plasmin-modified complexes partially containing fibrinopeptide A.
The m/z value variations of three standard peptides from 10 injections are 0.36, 0.89, and 0.26 Da for Angiotensin I, Fibrinopeptide B, and Angiotensin I at mean m/z 449.49, 786.24, and 433.23 Da, respectively.