Filtration surgery is currently one of the most effective methods to treat glaucoma; the objective of this surgery is the creation of a fistula at the limbus, which allows the aqueous humour to drain from the anterior chamber into the subconjunctival space, thereby circumventing any pathological obstruction to outflow.
All enrolled PG eyes had functional blebs in the first 6 months after the filtration surgery. At the end point of the study, 16 patients still had functional blebs with satisfactory IOP control, with one receiving PGA eye drop daily at night.
Laser iridotomy has been shown to be an effective primary therapy for early PACG, although advanced cases require further treatment with topical medication or filtration surgery. Unaffected fellow eyes of patients who have had angle closure have a 50% risk of developing an episode of angle closure if not treated with prophylactic iridotomy.
The technique of the filtration surgery has also undergone changes to enhance the success rate such as anti-fibrosing agents, releasable and adjustable sutures, laser suture lysis and non-penetrating procedures.