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 (ăn′tē-sī-kŏt′ĭk, ăn′tī-)
Counteracting or diminishing the symptoms of psychotic disorders, such as schizophrenia.
An antipsychotic drug.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Psychiatry) preventing or treating psychosis
(Pharmacology) any antipsychotic drug, such as chlorpromazine: used to treat such conditions as schizophrenia
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌæn ti saɪˈkɒt ɪk, ˌæn taɪ-)

1. of or pertaining to any of various drugs used in the treatment of psychosis, esp. schizophrenia, and severe states of mania, depression, or paranoia.
2. Also called neuroleptic. an antipsychotic drug.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.antipsychotic - tranquilizer used to treat psychotic conditions when a calming effect is desiredantipsychotic - tranquilizer used to treat psychotic conditions when a calming effect is desired
chlorpromazine, Thorazine - a drug (trade name Thorazine) derived from phenothiazine that has antipsychotic effects and is used as a sedative and tranquilizer
clozapine, Clozaril - an antipsychotic drug (trade name Clozaril) used as a sedative and for treatment-resistant schizophrenia; know to have few side effects
diphenylbutyl piperidine - a group of antipsychotic drugs used mainly in the treatment of schizophrenia
fluphenazine - tranquilizer used to treat psychotic disorders
Haldol, haloperidol - tranquilizer (trade name Haldol) used to treat some psychotic disorders and Tourette's syndrome
loxapine, Loxitane - a tranquilizer (trade name Loxitane) used to treat schizophrenia
Moban, molindone - antipsychotic drug (trade name Moban) used in the treatment of schizophrenia
prochlorperazine - antipsychotic and antiemetic drug used to treat schizophrenia and to combat nausea and vomiting
Mellaril, thioridazine - a tranquilizer (trade name Mellaril) used to treat schizophrenia and other psychotic disorders
Navane, thiothixene - a tranquilizer (trade name Navane) used to treat schizophrenia
antianxiety agent, ataractic, ataractic agent, ataractic drug, tranquilizer, tranquilliser, tranquillizer - a drug used to reduce stress or tension without reducing mental clarity
Eskalith, Lithane, lithium carbonate, Lithonate - a white powder (LiCO3) used in manufacturing glass and ceramics and as a drug; the drug (trade names Lithane or Lithonate or Eskalith) is used to treat some forms of depression and manic episodes of manic-depressive disorder
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


adj & n antipsicótico
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Typically, high-potency first-generation antipsychotics such as trifluoperazine and haloperidol are frequently associated with NMS as compared to the second-generation antipsychotics [1, 2].
Efficacy and safety of individual second-generation vs first-generation antipsychotics in first-episode psychosis: a systematic review and meta-analysis.
Reasons for switching from first-generation antipsychotic to second-generation antipsychotic
Major finding: Use of a first-generation antipsychotic agent was independently associated with a 3.76-fold increased risk of sudden cardiac death.
All the patients were prescribed antipsychotics; 60 (85.7%) patients had a trial on a first-generation antipsychotic, and only 10 (14.5%) were initiated on a second-generation antipsychotic de novo.
The study describes differences in patient characteristics and antipsychotic use patterns between those who received the two first-generation antipsychotic depot formulations and those who received oral formulations.
A link between schizophrenia and diabetes was postulated in the 1920s, (12) and a temporal association between first-generation antipsychotic drug treatment and hyperglycemia was first reported in the 1950s.
(6) Previously, in small placebocontrolled trials, the first-generation antipsychotic (FGA) pimozide was considered first-line treatment for this disease.
The CATIE Trial examined the effectiveness of a number of antipsychotics, comparing four second-generation antipsychotics (olanzapine, risperidone, quetiapine and ziprasidone) with perphenazine, a first-generation antipsychotic. (51) The most significant and unintended finding of this study (and a finding that has subsequently received a great deal of attention) was that 74% of subjects discontinued their treatment before the end of the study.
The investigators randomized patients to treatment with olanzapine, quetiapine, amisulpride, ziprasidone, or to the first-generation antipsychotic haloperidol.
First-generation antipsychotic drugs, as well as certain second-generation agents such as amisulpride and risperidone, are known inducers of hyperprolactinemia (Phan macotherapy 2009;29:64-73).
Whereas first-generation antipsychotic agents generally targeted dopamine, second-generation agents, or atypical antipsychotics, target specific receptor subtypes in the brain.