While testing 400 different plant extracts and flavonoids, researchers from the Salk Institute discovered that yerba santa contains the flavanone
sterubin, which has neuroprotective and anti-inflammatory effects.
Hesperetin (4'-methoxy-5.7.3'-trihydroxyflavanone) is the prominent flavanone
and its glycosides which can be found in citrus fruits.
Absorption, metabolism and excretion of flavanones
from single portions of orange fruit and juice and effects of anthropometric variables and contraceptive pilluse on flavanone
Health-promoting effects of the citrus flavanone
Anti MRSA activity achieved by flavanone
is beneficial to the structure of A ring (5,7-dihydroxylation) and B ring (2',4'- or 2',6'-dihydroxylation), which is essential for significant activity (40).
In second phase, docking studies on flavanone
derivatives were conducted.
A prenylated flavanone
from Dalea elegans inhibits rhodamine 6G efflux and reverses fluconazole resistance in Candida albicans.
With this background in mind, the current study analyzed the protective effects of Hsd , as a major flavanone
constituent, by determining its effect on 6-OHDA-mediated oxidative stress generation, mitochondrial dysfunction, and apoptosis in human neuroblastoma SH-SY5Y cells.
Jimenez-Ferrer et al., "Isosakuranetin-5-O-rutinoside: A New Flavanone
with Antidepressant Activity Isolated from Salvia elegans Vahl," Molecules, vol.
Agarwal, "Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone
silibinin with flavanolignan mixture silymarin," Oncogene, vol.
Hesperidin, a naturally occurring flavanone
glycoside, is mainly found in citrus fruits .
Kim, "A newprenylated flavanone
from the roots of Sophora flavescens," Fitoterapia, vol.