Dengue fever is a viral disease caused by positive sense single stranded ribonucleic acid (RNA) virus belonging to family Flaviviridae, genus Flavivirus
The genus Flavivirus
encompasses many relevant human pathogens, including yellow fever, dengue, West Nile Fever, Japanese encephalitis, and tick-borne encephalitis viruses.
Existen pruebas serologicas (ELISA, NP) para determinar anticuerpos IgM, pero hay el inconveniente de las reacciones cruzadas con otros flavivirus
Standards for defining individual members of the genus Flavivirus
(and indeed, for other virus genera) are still evolving, because the genetic sequence database is expanding.
Thirty (88%) of the 34 found to have evidence of flavivirus
also reported having an acute illness of some kind before the onset of neurologic symptoms.
Increased GBS incidence has been reported in countries with local transmission of Zika virus, a flavivirus
transmitted primarily by certain Aedes species mosquitoes (2).
Unknown also is the role of asymptomatic infection in the development of congenital infection or whether previous exposure to heterologous flavivirus
Excivion is a private UK company that has developed a proprietary antigen design platform for viral vaccines which it is applying to flavivirus
However, if either the Zika virus or dengue virus tests are positive or equivocal, then there is a presumptive recent Zika virus or dengue virus or Flavivirus
infection in the woman, at which point plaque reduction neutralization testing (PRNT) must be conducted.
ZIKV, a positive-sense, single-stranded RNA virus, member of genus Flavivirus
, family Flaviviridae, is another flavivirus
of a public health importance.
Their topics include host metabolism and its contribution in flavivirus
biogenesis, vector-borne bunyavirus pathogenesis and innate immune evasion, the role of inter-host and intra-host genetics in arbovirus evolution, the role of vertical transmission in mosquito-borne arbovirus maintenance and evolution, genetically modified vectors for controlling arboviruses, and small molecule drug development for dengue virus.
The Institute added that the Zika virus, which belongs to the Flavivirus
genus of viruses, has the RNA genome and is mainly transmitted through mosquitoes.