SDHA is a flavoprotein
and SDHB is an iron-sulfur protein; together they form the main catalytic domain that oversees the oxidation of succinate to fumarate.
In cancerous cells, there is over production of H2O2 that can be prevented by diphenyleneiodonium, which is an inhibitor of the flavoprotein
component of the NADPH-oxidase (Brown and Bicknell, 2001).
These cofactors are involved with flavoprotein
enzyme reactions and includes the activation of other vitamins (NIH-ODS 2018a).
In addition, mitochondria can cause caspase-independent apoptosis by releasing endonuclease G, death-modulating flavoprotein
, inhibitor of apoptosis protein, and Omi protein .
WST1 cytotoxic assay was performed to check yeast cell viability in the presence of geraniol, by a colorimetric method based on the principle of the metabolizing activity of mitochondrial succinic oxidase, cytochrome P-450 systems and flavoprotein
oxidase of living fungal cells (32,33).
chauvoei, such as enolase, chaperonin, ribosomal protein L10, flavoprotein
, and glycosyl hydrolase, which showed protective antigenicity in other bacteria.
Skeletal muscle magnetic resonance imaging of the lower limbs in late-onset lipid storage myopathy with electron transfer flavoprotein
dehydrogenase gene mutations.
Thus, there is decreased activity of Methylene tetrahydrofolate reductase enzyme which is a flavoprotein
enzyme important in Homocysteine metabolism and thus leads to hyperhomocysteinaemia.
Production of [O.sub.2.sup.*-] at complex I is particularly high during reverse electron transport (RET), which occurs when a high proton-motive force (Ap) develops across the inner mitochondrial membrane in conjunction with the pool of coenzyme Q (CoQ) being in a highly reduced state (i.e., mostly present as ubiquinol) as a result of electron transfer through complex II and electron transfer flavoprotein
:ubiquinone oxidoreductase (ETF-QO) [56-62].
NQO1, a cytosolic flavoprotein
, is involved in reactions of detoxification by maintaining the antioxidant forms of intermediate metabolites produced by monooxygenases and peroxidases .
The mitochondrial succinate dehydrogenase is a flavoprotein
in the mitochondrial inner membrane which can donate electrons to coenzyme Q10.