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A corticosteroid, C24H31FO6, administered by inhalation to treat asthma and nasally to treat allergies.

[flu(oro)- + (pred)nisol(one) + -ide.]


n flunisolida
References in periodicals archive ?
TABLE 2 Commonly used medications for nasal obstruction Category Medication Adult dose (18) Intranasal antihistamine azelastine 1-2 sprays BID olopatadine 2 sprays BID Oral antihistamine First generation diphenhydramine 25-50 mg q4-6 hours hydroxyzine 25-50 mg q6 hours chlorpheniramine 4 mg q4-6 hours Second generation loratadine 10 mg once daily cetirizine 10 mg once daily fexofenadine 180 mg once daily Intranasal glucocorticoids flunisolide 2 sprays once daily triamcinolone 2 sprays once daily budesonide 1 spray once daily bedomethasone 1-2 sprays twice daily fluticasone 2 sprays once daily mometasone 2 sprays once daily Leukotriene receptor antagonists montelukast 10 mg once daily
Among several commercially available steroid nasal sprays (Beclomethasone dipropionate, budesonide, flunisolide, fluticasone propionate, MF and triamcinolone acetonide), we chose to test MF for 4 reasons namely, (1) The drug had been reported previously not to cause any adverse tissue changes in the nasal mucosa of patients treated for long periods, (2) It has no effects on growth in children, (3) It has no effects on the hypothalamic-pituitary-adrenal axis (11) and (4) The systemic availability of the drug after topical administration is lower than that of other steroids.
therapeutic drug classes (antihistamines, bronchodilators - albuterol, epinephrine; combination drugs - Azelastine (benzalkonium chloride), Formoterol (budesonide), Salmeterol (fluticasone); Corticosteroids - beclomethasone, budesonide, flunisolide, fluticasone; decongestant sprays - phenylephrine and oxymetazoline hydrochlorides), and forecasts growth trends (CAGR% - 2016 to 2020).
Worldwide, seven ICS drugs are currently available: beclomethasone, budesonide, ciclesonide, flunisolide, fluticasone, mometasone and triamcinolone.
The participating children used beclomethasone, budesonide, ciclesonide, flunisolide, fluticasone, or mometasone, delivered by any type of inhalation device, and were followed for 3 months to 6 years.
Aerospan is an inhaler for the treatment of asthma that contains the active substance Flunisolide and is approved by the FDA.
Comparison of high-dose inhaled flunisolide to systemic corticosteroids in severe adult asthma.
However, Forest Laboratories not long ago introduced Aerospan an HFA form of flunisolide.
Only a few inhaled corticosteroid (ICS) products have the requisite median particle diameter (less than 2 mcm) needed to reach the alveolar tissue in the distal tracheobronchial tree, including beclomethasone dipropionate HFA (QVAR), flunisolide HFA (Aerospan), and ciclesonide (Sepracor).
Spahn Treatment Trends for Severe Asthma Current rate Historical rate Albuterol * (puffs/week) 34 72 Leukotriene-modifying agent 77% 0% Fluticasone/salmeterol * 66% 0% Budesonide 16% 2% Fluticasone * 16% l% Omalizumah 9% 0% Tiotropium 8% 0% Theophyline 8% n/a Mometasone * 3% 0% Beclomethasone HFA * 5% 0% Flunisolide * 0% 55% Triamcinolone * 0% 33% Beclomethasone CFC * 0% 15% * Statistically significant difference.
For example, with asthma, the primary treatment is an inhaled steroid such as flunisolide (Aerobid), but with COPD, the patient is usually placed on a bronchodilator, such as albuterol (Proventil), first.
The seven MDI drugs include: flunisolide (Forest's Aerobid), triamcinolone (Kos' Azmacort), metaproterenol (Boehringer Ingelheim's Alupent), pirbuterol (3M's Maxair), cromolyn (King's Intal), nedocromil (King's Tilade) and the combination of albuterol and ipratropium (Boehringer's Combivent).