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Related to fluvastatin: Fluvastatin sodium


A statin drug, C24H26FNO4, that blocks the body's synthesis of cholesterol and is used in the form of its sodium salt to lower cholesterol (especially LDL) levels and to reduce the risk of heart attack and stroke in individuals with elevated risk.

[flu(oro)- + -vastatin, statin suffix; see pravastatin.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.fluvastatin - least expensive statin drug (trade name Lescol); usually taken orally at bedtime
lipid-lowering medication, lipid-lowering medicine, statin, statin drug - a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase
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n fluvastatina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
A prospective study of paraoxonase gene Q/R192 polymorphism and severity, progression and regression of coronary atherosclerosis, plasma lipid levels, clinical events and response to fluvastatin. Atherosclerosis.
MEET THE STATINS EXAMPLES DOSAGE LDL (in milligrams) REDUCED High-Intensity Atorvastatin 40-80 mg (Lipitor[R]) 50% or Rosuvastatin 20-40 mg more (Crestor[R]) Moderate-Intensity Atorvastatin 10-20 mg Rosuvastatin 5-10 mg Simvastatin 20-40 mg (Zocor[R]) Pravastatin 40-80 mg (Pravachol[R]) Lovastatin 40-80 mg 30%-49% (Altoprev[R], Mevacor[R]) Pitavastatin 1-4 mg (Levalo[R]) Fluvastatin 40 mg (Lescol[R]) (twice daily) Fluvastatin XL 80 mg (Lescol XL[R]) Low-Intensity Simvastatin 10 mg Pravastatin 10-20 mg Less Lovastatin 20 mg than 30% Fluvastatin 20-40 mg Source: 2018 ACC/AHA Guideline on the Management of Blood Cholesterol, Circulation, Nov.
atorvastatin, simvastatin, fluvastatin, lovastatin) and 1,780 used water-soluble statins (e.g.
Statins are li pid-lowering drugs by c ompeti ti vely inhibiting 3-hydroxy-3-methyl-glutar yl-coenz yme A reductase enzyme (HMGCR) and thus limiting cholesterol biosynthesis.1 Statins are administered daily as standard therapy for primary and s eco ndar y prevention of coronary heart disease (CHD), stroke and peripheral ar terial disease (PAD).2 Commonly used statins are rosuvastatin, atorvastatin, fluvastatin, lovas tatin, simvastatin, pravastatin and pitavastatin.
Duration of statin use and type of statin (simvastatin, atorvastatin, fluvastatin, pravastatin, rosuvastatin) also varied.
In the event of recurrent symptoms after same-statin rechallenge, it's reasonable to switch to extended-release fluvastatin at 80 mg/day or low-dose rosuvastatin daily.
(Grapefruit is unlikely to boost the effects of fluvastatin, pravastatin, pitavastatin, or rosuvastatin, which are not metabolized by CYP3A4.)
Initially, the agreements cover one product from each partner, Diclofenac ER and Fluvastatin ER.
(30) to determine the mean percent change from baseline for lovastatin (10, 20, 40, and 80 mg), pravastatin (10, 20, and 40 mg), simvastatin (5, 10, 20, 40, and 80 mg), atorvastatin (10, 20, 40, and 80 mg), fluvastatin (20 and 40 mg), rosuvastatin (5, 10, 20, and 40 mg), and ezetimibe (10 mg; all daily doses).
Baehner et al., "Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer," Breast Cancer Research and Treatment, vol.