Site initiations and patient enrollment are underway in our XEN1101 Phase 2b clinical trial in adult focal epilepsy
. We have completed development of a new, pediatric-specific formulation of ezogabine known as XEN496.
Patients with focal epilepsy
respond well to surgical therapy one can remove the seizure focus.
Although demographic findings and etiology were consistent with the literature, CVT was reflected atypically in the clinic with focal epilepsy
. Mehvari Habibabadi et al.
 Studies have proven its effectiveness in the management of focal epilepsy
, as an adjuvant as well as monotherapy drug.
NEW ORLEANS -- Adults with focal epilepsy
experience a range of disturbing symptoms and functional impacts of the disease, according to a study presented at the annual meeting of the American Epilepsy Society The most prominent symptoms and effects on daily life might differ in the early, middle, and late stages of the disease, the results suggest.
The XEN1101 Phase 2b clinical trial is designed as a randomized, double-blind, placebo-controlled, multicenter study to evaluate the clinical efficacy, safety and tolerability of XEN1101 administered as adjunctive treatment in adult patients with focal epilepsy
. Approximately 300 patients will be randomized in a blinded manner to one of three active treatment groups or placebo.
A reduction of sleep spindles heralds seizures in focal epilepsy
. Clin Neurophysiol 2014;125:2207-2211.
MRI has been shown to be highly sensitive and specific in identifying the underlying pathology in focal epilepsy
Cole Thomson, six, has uncontrolled focal epilepsy
which is drug-resistant.
I was finally diagnosed with focal epilepsy
and photosensitive tendencies."
The medical notes reflect that after a head injury, claimant had experienced "recurrence of seizures in the 1st year mostly 'auras'" and "after the first year started to have his crying seizures." Claimant was diagnosed with focal epilepsy
. On May 5, 2017, a neurologist at the Cleveland Clinic opined that the crying spells were epileptic, but their relation to claimant's 2013 head injury was "not clear .
The other was an Australian cohort of 12 patients with focal epilepsy
who had at least 30 recorded seizures in a study of an implanted electrocorticography device that tracked them between 6 months and 3 years.