Antiepileptic Drugs Under Investigation for Treatment of Focal Epilepsy
M2 EQUITYBITES-June 23, 2017-Data reveals Zebinix has no significant negative consequences on neurocognitive function in children with focal epilepsy
presenting as a bath-induced paroxysmal event/breath-holding attack.
Temporal lobe epilepsy is a form of focal epilepsy
with seizures originating from the brain's temporal lobe.
The company is initially developing BIS-001 to treat refractory forms of focal epilepsy
, including refractory partial complex seizures and Dravet syndrome, a devastating refractory condition afflicting children.
Thornton R et al studied EEG correlated functional MRI was recorded in 76 patients undergoing presurgical evaluation and post-operative outcome in focal epilepsy
and the results showed the potential value of EEG and fMRI in presurgical evaluation.
The first demonstration phase provided genomic sequencing to 315 patients in the areas of hereditary neuropathy, focal epilepsy
, hereditary colorectal cancer, acute myeloid leukaemia and childhood syndromes.
Rasmussen encephalitis is an immune mediated brain disorder leading to unilateral hemispheric atrophy, intractable focal epilepsy
, and progressive neurological dysfunction.
Temporal lobe epilepsy (TLE) is the most common type of focal epilepsy
in clinic .
Conclusion: This study demonstrated that CBZ, OXC, and LEV are relatively effective in managing focal epilepsy
as measured by time to first seizure, 12-month remission rate, and retention rate.
Menstrual cycle worsening of epileptic seizures in women with symptomatic focal epilepsy
31-33) Of particular interest, the ability to trigger the fMRI acquisition based on real-time EEG monitoring may provide a more detailed understanding not only of the areas involved in certain physiologic events, eg, focal epilepsy
or cognitive processing, but also of the sequencing of the activation of the involved regions.