folliculin


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folliculin

(fɒˈlɪkjʊlɪn)
n
(Biochemistry) another name for oestrone
References in periodicals archive ?
Folliculin may play a role in repairing and re-forming lung tissue following damage.
85) Genetic predisposition to the development of ChRCC, particularly so-called hybrid oncocytic/chromophobe tumors that show overlapping features of oncocytoma and ChRCC, is seen in patients with Birt-Hogg-Dube syndrome, which is associated with germline folliculin (FLCN) mutations; these patients often develop multiple, bilateral, oncocytic renal neoplasms, including ChRCC, hybrid oncocytic/chromophobe tumors, and oncocytoma, and may also have characteristic skin (ie, fibrofolliculomas, trichodiscomas) and lung (ie, subpleural cystic blebs) findings.
There are several known kidney cancer genes: von Hipppel-Lindau (VHL), met proto-oncogene (hepatocyte growth factor receptor) (MET), folliculin (FLCN), Treacher Collins syndrome 1 (TSC1), Treacher Collins syndrome 2 (TSC2), fumarate hydratase (FH), succinate dehydrogenase (SDH), and protein polybromo-1 (PB1) also known as BRG1-associated factor 180 (BAF180) (PBRM1) (see Table 2) (Varela et al.
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