foreign body
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Related to foreign body giant cell: Touton giant cell
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Since giant cells are the key characteristic feature of GCM, the major differential diagnoses include other myocardial lesions containing giant cells such as infectious diseases, systemic granulomatous processes, and foreign body giant cell reaction.
Although foreign body giant cell reaction was not discovered, a mild tissue reaction in the form of fibrosis and a lymphocytic cell infiltration were reported.
There can be extensive foreign body giant cell reaction to the keratinous material and dystrophic calcification.
A foreign body giant cell reaction will contain giant cells, but not a mononuclear cell stroma.
By the mid-1980s, implant disruption, extensive fibrosis, massive foreign body giant cell reaction, and abundant histiocytic response were observed in this model of implant.
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