Abstract #2544: Non-Myeloablative Allogeneic Transplantation Resulting in Clinical and Molecular Remission with Low Non-Relapse Mortality (NRM) in Patients with Advanced Stage Mycosis Fungoides
(MF) and Sezary Syndrome (SS) Presenter: Wen-Kai Weng Session: 732.
Initially, lichen sclerosis et atrophicus, atrophoderma of Pasini-Pierini, sarcoidosis, mycosis fungoides
, post-inflammatory hyperpigmentation were considered in the differential diagnosis of our case.
Ceptaris developed and secured FDA approvals in August for the gel Valchlor (mechlorethamine) for early stage mycosis fungoides
, a type of cutaneous T-cell lymphoma.
Ayirici tanida nekrobiyozis lipoidika, lenfoma, granulomatoz rozase, lupus vulgaris, lepra, sifiliz, mikozis fungoides
, derin fungal enfeksiyonlar, yabanci cisim granulomlari bulunmaktadir (15-23).
Michael Krathen, MD, Clinical Assistant Professor of Dermatology at Stanford University, noted the ongoing clinical trial during a presentation at the annual meeting of the American Academy of Dermatology titled, "Case Based Discussions in Cutaneous Lymphomas: Treating early stage mycosis fungoides
Skin involvement differs from that seen in mycosis fungoides
and Sezary syndrome, with dermal infiltrates primarily around the appendages and without epidermotropism (7, 15).
and Sezary syndrome are known as the two most common forms of CTCL.
The SEER database classifies tumors of the external ear for coding and staging purposes under "Skin [excluding Skin of Eyelid] [excluding Malignant Melanoma, Merkel Cell Carcinoma, Kaposi Sarcoma, Mycosis Fungoides
, Sezary Disease, and Other Lymphomas].
In a sense, this is like delaying the diagnosis of mycosis fungoides
until the tumor stage is reached.
Sistemik veya kutanoz malin hastaliklara eslik etmesi nedeniyle paraneoplastik sendrom olarak kabul edenler oldugu gibi, mikozis fungoides
veya Sezary sendromundan farkli bir kutanoz T hucreli lenfoma ya da prelenfomatoz bir hastalik olarak kabul edenler de vardir (21), (22).
It still is used today for stage III and IV Hodgkin's disease and other hematologic cancers, including polycythemia vera and mycoses fungoides
, and bronchogenic carcinoma.
Molecular markers and prognostic factors in mycosis fungoides
, CD30+ T-cell lymphoproliferative disorders of the skin, and subcutaneous panniculitis-like T-cell lymphoma are some topics covered.