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Among the established agents, tubocurarine, gallamine, and pancuronium exert significant cardiovascular effects; atracurium and mivacurium produce minor changes in cardiovascular variables whereas vecuronium and rocuronium are associated with a high degree of cardiostability.
Gallamine was the first but its onset was long and duration was short.
Mushin reported clinical studies with the drug gallamine (7).
Gallamine (134) and alcuronium (135) are original ligands with such properties: gallamine suppresses the [[sup.
4 ml/1) and immobilized with an intramuscular injection of gallamine triethiodide (0.
They were anesthetized with ketamine hydrochloride (Ketaset, Butler Animal Health, Middletown, PA, dose[approximately equal to] 30 mg/kg) injected intramuscularly and paralyzed with the neuro-muscular blocking drug gallamine triethiodide (Flaxedil, Sigma Chemical Co.