Poloxamer 407/TPGS mixed micelles for delivery of gambogic
acid to breast and multidrug-resistant cancer.
Chen, "Inducing cell cycle arrest and apoptosis by dimercaptosuccinic acidmodifed [Fe.sub.3][O.sub.4] magnetic nanoparticles combined with nontoxic concentration of bortezomib and gambogic
acid in rpmi-8226 cells," International Journal of Nanomedicine, vol.
acid grafted low molecular weight heparin micelles to combine anti-tumor effect of gambogic
acid with antiangiogenic and anti-metastatic effect of heparin .
Synthesis and evaluation of gambogic
acid derivatives as antitumor agents.
acid induced oxidative stress dependent caspase activation regulates both apoptosis and autophagy by targeting various key molecules (NF-[kappa]B, Beclin-1, p62 and NBR1) in human bladder cancer cells," Biochimica et Biophysica Acta, vol.
acid, a natural product inhibitor of Hsp90," Journal of Natural Products, vol.
MNPs-Fe[sub]3O[sub]4 have been successfully loaded with doxorubicin,[sup], wogonin,[sup], and gambogic
acid.[sup], All demonstrated that MNPs-Fe[sub]3O[sub]4 could increase the intracellular drug accumulation for cancer cells, thus improving the anticancer effects of the drug.
Synthesis and antiangiogenic activity of novel gambogic
acid (GA) has anticancer effect and anti-proliferative activity which is extracted from a dried yellow resin of the Garcinia hanburyi Hook.f.
Other spice-derived phytochemicals, such as capsaicin, cardamonin, dibenzoylmethane, diosgenin, gambogic
acid, gingerol, thyoquinone, urosolic acid and zerumbone have been show the ability to suppress NF-kB activation in a similar manner.
Yu et al., "Posttranscriptional regulation of the telomerase hTERT by gambogic
acid in human gastric carcinoma 823 cells," Cancer Letters, vol.
Zhao et al., "Gambogic
acid reduced bcl-2 expression via p53 in human breast MCF-7 cancer cells," Journal of Cancer Research and Clinical Oncology, vol.