gamma-hydroxybutyrate


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gam·ma-hy·drox·y·bu·ty·rate

 (găm′ə-hī-drŏk′sē-byo͞o′tə-rāt′)
n. Abbr. GHB
A compound, C4H8O3, similar in structure and function to gamma-aminobutyric acid, usually used in the form of its sodium salt. It is prescribed to treat certain symptoms of narcolepsy and is used illegally for its euphoric and sedative effects.
Translations

gamma-hydroxybutyrate, gamma-hydroxybutyric acid (GHB)

n gamma-hidroxibutirato, ácido gamma hidroxi-butírico, éxtasis líquido (fam)
References in periodicals archive ?
[USA], Oct 9 (ANI): According to a new research, regular use of the party drug GHB (Gamma-hydroxybutyrate), which is often placed in alcoholic beverages, is associated with brain changes including negative effects on long-term memory, working memory, IQ, and higher levels of stress and anxiety.
GHB stands for gamma-Hydroxybutyrate drug, commonly known as liquid ecstasy or simply, 'G.'
A detailed history of past or current substance use was obtained, including cannabis, MDMA (methylenedioxymethamphetamine), GHB (gamma-hydroxybutyrate), crystal methamphetamine, cocaine, CAT (methcathinone), liquid MDMA (liquid E), heroin and methaqualone.
Baclofen, a GABA-B agonist, similar to phenibut, blocks voltage-gated calcium channels; however it does not have affinity for the gamma-hydroxybutyrate (GHB) receptor; therefore abuse potential is minimal [9].
(NASDAQ: ALDX) presented novel data at the American Society of Human Genetics 2017 annual meeting demonstrating that ADX-102 reduced levels of gamma-hydroxybutyrate (GHB) and gamma-aminobutyrate (GABA) in a knockout mouse model of Succinic Semialdehyde Dehydrogenase (SSADH) deficiency, the company said.
(https://www.ncbi.nlm.nih.gov/pubmed/17011713) BHB is almost identical to GHB , the naturally occurring neurotransmitter, called gamma-hydroxybutyrate, that in synthetic form is used as a (https://theconversation.com/weekly-dose-ghb-a-party-drug-thats-easy-to-overdose-on-but-was-once-used-in-childbirth-73266) recreational drug.
Drugs commonly involved as date-rape drugs are hypnotic or can lead to amnesia: benzodiazepines, gamma-hydroxybutyrate and its derivates or ketamine (Scott-Ham & Burton 2005; Hurley, Parker & Wells 2006; Jansen & Theron 2006).
Biopharmaceutical company Jazz Pharmaceuticals plc (NasdaqGSJAZZ) revealed on Tuesday the receipt of the US patent related to the use of Xyrem (sodium oxybate) oral solution for the treatment of narcolepsy, titled 'Microbiologically Sound and Stable Solutions of Gamma-Hydroxybutyrate Salt for the Treatment of Narcolepsy'.
These include 3,4 methylenedioxymethamphetamine (MDMA or ecstasy), gamma-hydroxybutyrate (GHB) and ketamine.
(1) In this article we focus on G, the collective term for gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL).
National Institute on Drug Abuse (NIDA) in its "Community Alert on Club Drugs," defined "club drugs" as Ecstasy (3,4-methylenedioxymethamphetamine, or MDMA), gamma-hydroxybutyrate (GHB), ketamine, Rohypnol (flunitrazepam), methamphetamine, and lysergic acid diethylamide (LSD) (3).

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