The publication entitled, "Effects of Varying Intranasal Treatment Regimens in ST266-Mediated Retinal Ganglion Cell
Neuroprotection," details the preclinical study exploring the neuroprotective effects of daily and twice daily intranasally delivered ST266 to evaluate different treatment regimens an EAE-induced experimental ON mouse model.
In a similar study conducted by Sohn EH and associates, it was revealed that patients with DM but no diabetic retinopathy had thin ganglion cell
layer and RNFL, as compared to age matched control group.
If an abnormally high frequency of larger (more ganglion cell
profiles per ganglion) submucosal ganglia is the only obligate diagnostic criterion for IND B, it should be possible to develop a formalin-fixed, paraffin-embedded tissue approach with properties similar to those of the LDH enzyme histochemistry/frozen section method that underlies the 2006 Meier-Ruge criteria.
The pigeon retina: quantitative aspects of the optic nerve and ganglion cell
populations in normal and pathological human cochleae implications for cochlear implantation.
Because OCT technology significantly enhances the imaging resolution, the segmentation of retinal layers, such as the ganglion cell
layer (GCL), inner plexiform layer (IPL), and retinal nerve fiber layer (RNFL), is now possible.
Using an optical coherence tomographic angiography system, automated measurements of retinal nerve fiber layer thickness, ganglion cell
layer thickness, inner and outer foveal thickness, vascular density, macular volume, and foveal avascular zone were collected for both eyes.
The SD-OCT parameters of the retinal nerve fiber layer (RNFL) and ganglion cell
complex were analyzed statistically using the receiver operating characteristic curve and area under the curve (AUC).
By contrast, retinal ganglion cell
responses to light stimuli were observed in 3 transplanted retinas out of 7 that were measured.
At earlier stages, drug accumulates in the cytoplasm of RGCs and, leads to cell shrinkage and formation of an irregular nucleus, which eventually results in ganglion cell
Microscopy of the biopsied gastric mass was interpreted to be a ganglioneuromatous proliferation with small foci in the lamina propria of spindled cells in fascicles with slightly atypical nuclei, positive on S100 protein and SOX-10 immunohistochemically stained tissue sections (Figures 3(a) and 3(b) a single, well-formed ganglion cell
was noted in one of the areas of spindle cells, positive for neuron specific enolase (NSE) by immunohistochemistry (Figures 4(a) and 4(b)).
The aim of our study was to assess retinal and choroidal thickness and ganglion cell
complex in pubescent T1D children.