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Related to gelsolin: Profilin


A calcium-regulated actin-binding protein that breaks cytoskeletal actin filaments into smaller pieces, thus transforming the actin network (or gel) into a colloidal solution and influencing cell morphology, motility, and apoptosis.

[gel + sol (since it works upon actin to transform cytoplasm from a gel to a sol) + -in.]
References in periodicals archive ?
Chan Harvard School of Public Health demonstrated clinical improvement in mice infected with pneumococcal organisms even in the absence of antibiotic treatment and after delaying gelsolin administration.
T-platin, gelsolin) Matrix synthesis factors (e.g., collagen-binding protein 2) Membrane proteins (e.g., [99] annexin A6, annexin A2) Metabolic enzymes (e.g., thioredoxin reductase, transaldolase, and malate dehydrogenase)
Gelsolin is a calcium-activated actin-binding protein and plays important roles in F-actin severing, capping, and nucleation [40, 41].
Plasma gelsolin and circulating actin correlate with hemodialysis mortality.
She was diagnosed with Meretoja's syndrome at the age of 50 after a bilateral facial paresis and the diagnose was confirmed by the presence of gelsolin mutation (G654A).
Other identified spots included gelsolin, vimentin, gamma enolase, ATP synthase and cytoskeletal protein.
Song et al., "Clic1 plays a role in mouse hepatocarcinoma via modulating Annexin A7 and Gelsolin in vitro and in vivo," Biomedicine and Pharmacotherapy, vol.
The purpose of the present study was to evaluate caspase-3 and gelsolin levels in cerebrospinal fluid (CSF) and plasma associated with secondary damage after SCI, and to evaluate the effects of methylprednisolone and sildenafil on caspase-3 and gelsolin levels as markers of neuroprotection after SCI.
These polypeptides include both intrinsically disordered polypeptides such as the A[beta] peptide [83], [alpha]-synuclein [84], and IAPP [72] and natively folded proteins such as transthyretin [85], gelsolin [86], and [beta]2-microglobulin [87].
Chauhan, "Anti-amyloidogenic, antioxidant and anti-apoptotic role of gelsolin in Alzheimer's disease," Biogerontology, vol.