genus Tabernaemontana

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Noun

genus Tabernaemontana - evergreen tropical trees and shrubs with milky sap

dicot genus, magnoliopsid genus - genus of flowering plants having two cotyledons (embryonic leaves) in the seed which usually appear at germination

Apocynaceae, dogbane family, family Apocynaceae - chiefly tropical trees or shrubs or herbs having milky juice and often showy flowers; many are sources of drugs

Adam's apple, coffee rose, crape jasmine, crepe gardenia, crepe jasmine, East Indian rosebay, Nero's crown, pinwheel flower, Tabernaemontana divaricate - tropical shrub having glossy foliage and fragrant nocturnal flowers with crimped or wavy corollas; northern India to Thailand

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The genus Tabernaemontana has evoked interest due to the important biologic activity of its extracts, particularly, antimicrobial [5, 6], anti-tumoral [7], antioxidant [8], anti-cholinesterasic [9], and anti-inflammatory [10] activities, most of which have been associated with indole alkaloids.

The results obtained in this study, also considering previous reports of the genus Tabernaemontana [17, 20], indicated the presence of the following alkaloids: 16-epi-affinine (m/z 325.1911), coronaridine-hydroxyindolenine (m/z 355.2019), voachalotine (m/z 367.2020), voacristine-hydroxyindolenine (m/z 401.2072), 12-methoxy-n-methyl-voachalotine (m/z 411.2280), and of an unidentified compound with m/z 385.2125, whose fragmentation profile suggested a derivative of voacristine or voacangine.

These results corroborate previous reports that mentioned the anticholinesterase potential of alkaloids found in the genus Tabernaemontana and the possibility of using these compounds for studies involving the treatment of neurodegenerative diseases [9, 24].

Chemical constituents antioxidant and anticholinesterasic activity of Tabernaemontana catharinensis

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