germ line


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Related to germ line: germ layer, Germline mutation

germ·line

or germ line  (jûrm′līn′)
n.
1. The gamete-producing cells in a sexually reproducing organism, by means of which genetic material is passed on to subsequent generations.
2. The collection or sequence of such cells in an individual and all its descendants.

germ line

n
(Genetics) the lineage of cells culminating in the germ cells
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References in periodicals archive ?
Though gene-editing tools potentially have the power to cure a number of diseases, scientists have proceeded with deliberate care, in part to avoid introducing unintended mutations into the germ line (cells that become eggs or sperm).
Evaluation of cell death in the female germ line and identification of the proportion of each type of cell death can provide a basis for the provision of new methods to delay menopause time.
The news stunned the scientific community on the eve of the Hong Kong summit, not least because it breached the scientific consensus that editing the human germ line -- that is, the genetic material that can be passed down to future generations -- is unethical.
Part II will appear in the January 2019 issue with an update by Gao et al on the clinical, pathologic, and molecular characterization of myeloid neoplasms with germ line predisposition, emphasizing the important features that will help practicing pathologists to recognize these newly described entities.
Cross-tissue comparison: As a subsidiary finding, comparison of neoplastic tissues and blood of the same diseased animal were compared, in which Tp53 gene was amplified in one of the mammary tumor sample (DP5) to ascertain the comparison of mutational variations in blood and tumorous tissues of the animal to have an idea of germ line and somatic transmitted mutations.
DNA from the metastatic biopsies was characterized by exome capture and sequencing, and it was then compared to exome data from a matched normal tissue of each patient (white blood cells or cheek swabs) to identify somatic and germ line mutations in each patient.
And she confessed that unlike many scientists in her field she steadfastly disagreed with editing the human "germ line" - the cells that pass inherited genes from one generation to the next.
And she confessed that, unlike many scientists in her field, she steadfastly disagreed with editing the human "germ line" - the cells that pass inherited genes from one generation to the next.
Therefore, we extracted condition medium from adult mouse Sustentacular cells at different time intervals to evaluate its effect on the induction of BMMSCs to express male germ cell markers and differentiate into male germ line cells.
"Testing the Mitochondrial genome, which is transmitted exclusively through the female germ line, makes it possible to identify relatives," Rabbi Yosef Carmel, the Rabbinical Dean of the Eretz Hemdah Institute for Advanced Jewish Studies, told the Israeli newspaper Makor Rishon.