germinoma


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Translations

ger·mi·no·ma

n. germinoma, neoplasma de tejido o células germinales usualmente localizado en los testículos u ovarios.

germinoma

n germinoma m
References in periodicals archive ?
Therefore, autoimmune pituitary hypophysitis should always be considered in the work-up and differential diagnosis of non-functioning lesions involving the pituitary gland.13-15 Moreover, other inflammatory/ infectious disorders of pituitary gland as well as rare tumors like Germinoma also pose diagnostic dilemma, which can only be definitely diagnosed through transphenoidal biopsy of pituitary gland.
Comparative analysis of germ cell transcription factors in CNS germinoma reveals diagnostic utility of NANOG.
The initial treatment of prolactin-secreting adenomas was dopaminergic agonists, rather than neurosurgery.[6] Adrenocorticotropic hormone-secreting adenomas accounted for approximately 12.28% of all pituitary adenomas in the CPDRN, which is higher than the 1-7% reported in Finland; this outcome is related to PUMCH's expertise in Cushing's disease, which affects patients' choice of hospital.[6] Craniopharyngioma (95, 0.66%), Rathke's clef cysts (74, 0.51%), hypophysitis (6, 0.04%), germinoma (3, 0.02%), pituitary carcinoma (44, 0.31%), and diabetes insipidus (1, 0.01%) were in the minority diagnoses, while no cases of histiocytosis have been entered in the registry [Table 1].{Table 1}
Meningioma, astrocytoma and germinoma: case presentations of three intracranial tumors.
In pediatric patients, the most common CNS tumor types leading to ENM were: medulloblastoma (56.3%), germinoma (9.8%), glioblastoma (6.9%), ependymoma (3.7%) and pilocytic astrocytoma (2.9%) [6].
Two cases (6.45%) constituted germ cell tumours, which included one case of primary thymic germinoma and immature teratoma each respectively.
These tumors are called seminoma when present in the testis, dysgerminoma when present in the ovary, and germinoma when found in an extragonadal site.
Primary intracranial germ cell tumors (GCTs) are 3.1% of all primary brain tumors [1]; they affect pediatric population (mean age of 16.1 years) with a male:female ratio of 4:1 and are located in midline structures such as suprasellar and/or pineal region [2]; tumors contemporary located at suprasellar and pineal regions called synchronous GCT are 13% of all GCTs; these lesions are germinoma (60-80% of patients) with high sensitivity to radiotherapy [3], teratoma (18%), endodermal sinus tumors (7%), embryonal carcinomas (5%), and choriocarcinomas (5%).
The tissue was positive for an intrasellar pituitary germinoma, confirmed by positive human chorionic gonadotropin (hCG) staining, C-kit, and placental alkaline phosphatase (PLAP) (Figure 2).
OCT4 is a sensitive and specific marker for diagnosing seminoma, dysgerminoma, germinoma, and embryonal carcinoma [2].
Other diagnoses that should be considered are tumors that occur more commonly in the suprasellar region, such as germinoma or eosinophilic granuloma [9].