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Related to ghrelin: PYY


A hormone that is secreted by cells in the stomach and promotes hunger before an expected meal, decreases in amount after eating, and promotes secretion of growth hormone.

[Coined by its discoverers from ghrē-, reconstructed Proto-Indo-European root of English grow; see grow + -in (probably influenced by g(rowth)-h(ormone)-rel(easing peptide), a description of ghrelin's function and chemical composition).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) a hormone produced in the body that stimulates appetite
[C20: from g(rowth) h(ormone) rel(easing) + -in]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ghrelin - a gastrointestinal hormone produced by epithelial cells lining the fundus of the stomach; appears to be a stimulant for appetite and feeding, but is also a strong stimulant of growth hormone secretion from the anterior pituitary
gastrointestinal hormone, GI hormones - hormones that affect gastrointestinal functioning
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References in periodicals archive ?
After centrifugation of blood sample, these were analysed for ghrelin hormone levels by using full-automated ELISA.
Soft and hard tissues homeostasis, destruction, and healing are not only regulated by inflammation but also by hormones such as ghrelin (GHRL).
Ghrelin is an acylated peptide which contains 28 amino acids and it is primarily produced in the stomach and the proximal small intestine (4).
Ghrelin, one of the hormones playing a role in the pathogenesis of IBS, is a 28-amino acid lipopeptide hormone produced in the enteroendocrine X/A-like cells of the gastric oxyntic gland mucosa (6).
Two hormones, leptin and ghrelin, are known to trigger the body to eat in a weight-loss setting.
Ghrelin Improves the Fine Structure of Atrial Natriuretic Factor (ANF) Granules and Intercalated Disc Junctions in Experimentally-Induced Myocardial Infarction in Rats
Interstitial cells of Cajal (ICC), expression of stem cell factor (SCF), ghrelin, and endothelin-1 play important roles in intestinal motility (12-14).
RM-853 is a potent, orally available ghrelin o-acyltransferase inhibitor currently in preclinical development for Prader-Willi Syndrome.
Ghrelin, the endogenous ligand for the GH-secretagogue receptor (GHS-R), has been found in the testes of many vertebrates, and in the cerebellum and gastrointestinal tract of African ostrich, but there is little known about its distribution in the testes of the African ostrich.
Ghrelin, originally identified as a growth hormone secretagogue with orexigenic and lipogenic effects, has also been shown to play significant roles in glucose regulation.
In physiological conditions, ghrelin levels raise in anticipation of a meal and decrease during the postprandial period [19].
Cholecystokinin also acts to decrease the hunger-promoting hormone in the body called ghrelin.