Magnetic Resonance Imaging (MRI) with and without contrast showed mild parenchymal loss which was disproportionate to the patient's age, bilateral symmetrical cavitary lesions in the globus pallidus
When the DBS is indicated for the treatment of various dystonic syndromes, the globus pallidus
internus (GPi) is most often used as a therapeutic target.
Involvement of globus pallidus
and midbrain nuclei in pantothenate kinase-associated neurodegeneration: measurement of T2 and T2* time.
We performed globus pallidus
internus (GPi) DBS on 25 patients with drug-resistant TS and conducted follow-up assessments of 24 of the patients for over 1 year.
The physiological effect of lesioning or deep brain stimulation (DBS) on these nuclei is still unknown, but the most likely explanation is that the damping effect of PD is alleviated by high-frequency stimulation of the STN, while the inverse happens in dystonia, where stimulation of the globus pallidus
interna (GPi) dampens the abnormal tone and movements.
hypointensity with or without central hyperintensity is highly characteristic of PKAN (15) (Pantothenate Kinase-Associated Neuropathy) or Hallervorden-Spatz disease.
A1] - globus pallidus
Hyperintensity of pyramidal tractus [+.
1,7) In contrast, infarction of the globus pallidus
due to stroke is typically unilateral and follows a vascular distribution rather than being contained by the neuroanatomic boundary.
Specifically, the neurons of the striatum extend to the internal globus pallidus
(direct pathway), the external globus pallidus
(indirect pathway), and the substantia nigra (indirect pathway).
Differential expression of DSCR in human brain A quantitative analysis of global transcription of DSCR genes along the structures of the brain nuclei and the limbic lobe revealed that the highest values of z-score were registered in the area that includes the putamen for DSCR3, RCAN1 as well as in left and right caudate nuclei for DSCR6, and the left and right globus pallidus
for DSCR3, SH3GBR, DYRK1A, CLIC6 and PRMT2.
The caudate nucleus, red nucleus, globus pallidus
, putamen, white matter, thalamus and substantia nigra of brain were drawn manually based on their anatomical locations in Signal Processing in Nuclear Magnetic Resonance (SPIN).
Intriguingly, salience experience alters the activity in the medial globus pallidus
of the basal ganglia and the lateral habenula (LHb) as well as in dopamine and serotonin neurons.