glucocorticoid


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Related to glucocorticoid: mineralocorticoid, Glucocorticoid receptor

glu·co·cor·ti·coid

 (glo͞o′kō-kôr′tĭ-koid′)
n.
Any of a group of steroid hormones, such as cortisol, that are produced by the adrenal cortex, are involved in carbohydrate, protein, and fat metabolism, and have anti-inflammatory properties.

[Shortening of glucocorticosteroid.]

glucocorticoid

(ˌɡluːkəʊˈkɔːtɪˌkɔɪd)
n
(Biochemistry) any of a class of corticosteroids that control carbohydrate, protein, and fat metabolism and have anti-inflammatory activity

glu•co•cor•ti•coid

(ˌglu koʊˈkɔr tɪˌkɔɪd)

n.
any of a class of steroid hormones that are produced by the adrenal cortex under conditions of stress and that inhibit immunologic reactions.
[1945–50]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.glucocorticoid - a steroid hormone that is produced by the adrenal cortex of animals; affects functioning of gonads and has anti-inflammatory activity
endocrine, hormone, internal secretion - the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect
corticosterone - secreted by the adrenal cortex; involved in regulating water and electrolyte balance in the body
adrenal cortical steroid, corticoid, corticosteroid - a steroid hormone produced by the adrenal cortex or synthesized; administered as drugs they reduce swelling and decrease the body's immune response; "adrenal cortical steroids are used to treat many different conditions"
Pediapred, prednisolone, Prelone - a glucocorticoid (trade names Pediapred or Prelone) used to treat inflammatory conditions
Deltasone, Liquid Pred, Meticorten, Orasone, prednisone - a dehydrogenated analogue of cortisol (trade names Orasone or Deltasone or Liquid Pred or Meticorten); used as an anti-inflammatory drug in the treatment of arthritis and as an immunosuppressant
Translations

glu·co·cor·ti·coid

n. glucocorticoide, grupo de hormonas segregadas por la corteza suprarrenal que intervienen en el proceso metabólico del organismo y tienes un efecto antiinflamatorio.

glucocorticoid

adj & n glucocorticoide m
References in periodicals archive ?
These observations support the role of appropriately timed exogenous glucocorticoid therapy to replenish the deficient cortisol and provide a balance between the pathological circadian mismatch between cytokine and glucocorticoid production5.
South San Francisco, California-based cancer therapy company Oric Pharmaceuticals has dosed the first subject with Oric-101, a potent small molecule inhibitor of the glucocorticoid receptor (GR), in a Phase 1a clinical study, the company said.
UK's Medicines and Healthcare products Regulatory Agency (MHRA) has granted Raxone (idebenone) a positive scientific opinion through the Early Access to Medicines Scheme (EAMS) for patients with respiratory function decline not taking glucocorticoids in Duchenne Muscular Dystrophy (DMD).
This study was sponsored by the Glucocorticoid Low-Dose Outcome in RA Project of the European Commission's Horizon 2020 Initiative.
The data indicated that treatment with Prolia for 12 months, compared to risedronate, led to significantly greater gains in bone mineral density at the lumbar spine and total hip, both in patients receiving continuing glucocorticoid therapy and in patients newly initiating glucocorticoid therapy.
Offspring with at least one parent with PTSD "displayed low urinary and plasma cortisol levels, and increased glucocorticoid responsiveness as measured by plasma cortisol levels in response to low dose dexamethasone administration [a test to assess adrenal function]," compared with those whose parents did not have PTSD.
Unlike some natural steroid hormones synthesised in the adrenal cortex, FA is a synthetic glucocorticoid, and was shown to have stronger effects in activating the cellular receptor for glucocorticoids, which are already used for numerous clinical applications.
While the current study does not propose using glucocorticoid pills right away, it opens the path for using glucocorticoid therapy along with light therapy to better synchronise the biological clock in people.
Glucocorticoids appear to play a central role in transmitting these signals.
In the presence of Dex + Gen, GR association with the chromatin at the GRE -1919 to -1794 and the transcriptional start site were reduced, offering a potential mechanism by which glucocorticoid-mediated up-regulation of GILZ mRNA was antagonized by the presence of Gen and glucocorticoids.
Adding the glucocorticoid, Kidsolone, to the basal tension had a negligible effect [Figure 1].
The impact of glucocorticoid hormones on lipoprotein metabolism can be examined in normal variation, acute and chronic dosing, replacement therapy, and hypercortisolism.

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