glucokinase


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glucokinase

(ˌɡluːkəʊˈkaɪneɪz)
n
(Biochemistry) biochem an enzyme that regulates carbohydrate metabolism

glu•co•ki•nase

(ˌglu koʊˈkaɪ neɪs, -neɪz)

n.
an enzyme that catalyzes the phosphorylation of glucose.
[1950–55]
References in periodicals archive ?
Glucokinase gene expression is nutritionally regulated in liver of gilthead sea bream (Sparus aurata).
Chronic ethanol consumption-induced pancreatic [beta]-cell dysfunction and apoptosis through glucokinase nitration and its down-regulation.
Facilitating effects of berberine on rat pancreatic islets through modulating hepatic nuclear factor 4 alpha expression and glucokinase activity.
Differential regulation of glucokinase activity in pancreatic islets and liver of the rat.
Peroxisome proliferator-activated receptor-[gamma](PPAR[gamma]) is a nuclear hormone receptor that maintains homeostasis of glucose by activating glucokinase and glucose transporter 2 (GLUT2) in the liver and pancreas.
2001) Glucokinase is highly induced and glucose-6-phosphatase poorly repressed in liver of rainbow trout (Oncorhynchus mykiss) by a single meal with glucose.
Tiedge, "Interaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) with glucokinase activates glucose phosphorylation and glucose metabolism in insulin-producing cells," Diabetes, vol.
In July 2014, Lilly and Yabao also announced the co-development of Lilly's glucokinase activator (GKA), LY2608204.
The mechanism is not fully understood but it is known that fructose-1-phosphate (a metabolite formed in the liver by fructokinase that phosphorylates quickly fructose, using a molecule of ATP), has the ability to dissociate glucokinase from glucokinase regulatory protein (GKRP).
SAN DIEGO -- The two main things to understand about maturity-onset diabetes of the young due to mutations in the glucokinase gene are that this form of diabetes is far more common than you probably realize, and--unique in the world of diabetes--no treatment is warranted, according to Dr.
SAN DIEGO--The two main things to understand about maturity-onset diabetes of the young due to mutations in the glucokinase gene are that this form of diabetes is far more common than you probably realize, and--unique in the world of diabetes--no treatment is warranted, according to Dr.
The supernatant was separated and divided into three parts for measurement of glucokinase (GK), phosphoenolpyruvate carboxykinase (PEPCK), and glucose-6-phosphatase (G6Pase) activity.