Reliable markers for HCC diagnosis are aspartate transaminases (AST) and alanine transaminases (ALT) (Whittby et al., 1984), lactate dehydrogenase (LDH) (King, 1965), bilirubin (Harper, 1961), Gamma-glutamyl transferase (GGT) (Yao et al., 2004), alpha feto protein (Sell and Becker, 1978), 5-nucleotidase (5NT) (Sadej et al., 2006), Glucose-6-phosphate dehydrogenase
(G6PDH) (Molero et al., 1994) and albumin (Vandenberghe, 1996).
Large doses of Vitamin C have resulted in hemodialysis in patients with glucose-6-phosphate dehydrogenase
deficiency,' the FDA said.
A 54-year-old man with metastatic prostate cancer and glucose-6-phosphate dehydrogenase
(G6PD) deficiency developed severe hemolytic anemia and acute renal failure after receiving 30 g of vitamin C intravenously, followed by 60 g four days later.
Issues with primaquine (i.e., CYP2D6poor metabolizers or hemolysis risk in patients with glucose-6-phosphate dehydrogenase
deficiency) complicate treatment of dormant hypnozoites that cause relapse (1).
Ministry of Health - Oman states that 75 per cent of patients visiting healthcare centres have blood-inherited disorders such as sickle cell disease, thalassemia and glucose-6-phosphate dehydrogenase
Keywords: Glucose-6-phosphate dehydrogenase
, G6PD, Hepatitis E, Haemolysis.
Henna tattoos should be avoided in small children and in persons with glucose-6-phosphate dehydrogenase
(G6PD) deficiency, as henna is a potent oxidant of G6PD-deficient cells.
On the other hand, low levels of erythrocyte protective factors, antioxidants and indirect antioxidant enzymes (superoxide dismutase, glutathione peroxidase, reduced glutathione and decreased activity of glucose-6-phosphate dehydrogenase
) have reportedly been associated with this condition, however, phosphorus deficiency has most consistent association with PHU (MacWilliams, 1982;Singariet al.,1991; Heuer and Bode,1998; Chhabra et al.,2015).
Specialist investigations for non-immune haemolysis were performed, namely Hb electrophoresis, glucose-6-phosphate dehydrogenase
screen and unstable Hb analysis, which were all within normal limits.
(G6PDH) activity was ordered on a 3-day-old term male neonate.
by Madiha Asif/ [email protected] Transmitted genetically: The most common hereditary blood disorders in Oman are sickle cell disease, beta thalassemia and glucose-6-phosphate dehydrogenase
(G6PD) deficiency is the commonest enzyme deficiency in humans, especially in those of African descent , with a prevalence of 400 million affected people worldwide .