glucuronic acid

(redirected from glucuronate)
Also found in: Medical, Encyclopedia.

glucuronic acid

(ˌɡluːkjʊˈrɒnɪk)
n
(Chemistry) chem a soluble compound derived from glucose. Formula C6H10O7

glu′cu•ron′ic ac′id

(ˈglu kyəˈrɒn ɪk, ˌglu-)
n.
an acid, C6H10O7, formed by the oxidation of glucose, found combined with other products of metabolism in the blood and urine.
[1910–15]
Translations

glu·cu·ron·ic ac·id

n. ácido glucurónico, ácido de efecto desintoxicante en el metabolismo humano.
Mentioned in ?
References in periodicals archive ?
conjugation reactions" that increase water solubility of a drug with a polar moiety glucuronate, acetate, and sulfate, respectively (11)
Liver accepts and metabolises organophosphates through oxidation and sulfate or glucuronate conjugation and may undergo oxidative damage in case of organophosphorus poisoning.
Despite the presence of three phenolic hydroxyl groups attached to C-5, C-11, and C-12 on the coumestan skeleton of WEL, a glucuronate conjugate was preferentially formed (Huang 2015).
Metabolites conjugated with methyl, glucuronate, and sulfate groups are the predominant forms present in plasma.
Trimetrexate glucuronate (with Leucovorin)(Neutrexin, TMTX), U.
The mammalian lignans, enterodiol and enterolactone, can be excreted directly in the feces, or after being absorbed in the gut, they enter the enterohepatic circulation where they are conjugated with glucuronate, and then excreted in urine and bile [10,11].