glycosylation


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gly·co·sy·la·tion

 (glī′kō-sĭ-lā′shən)
n.
The addition of saccharides to proteins or lipids to form a glycoprotein or glycolipid.

[glycose, a monosaccharide (variant of glucose) + -yl + -ation.]

gly·co′sy·late′ v.

glycosylation

(ˌɡlaɪkəʊsəˈleɪʃən)
n
(Biochemistry) the process by which sugars are chemically attached to proteins to form glycoproteins
[from glycosyl radical derived from glycose + -ation]
References in periodicals archive ?
On the other hand, the complexity of the glycan structures, the multiple substitutions at glycosylation sites, and the structural diversity associated with the protein backbone posed a giant challenge for the glycoprotein analysis.
The importance is clear when you realize that more than half of the approved biopharmaceuticals are glycosylated and that regulators around the world require glycosylation characterization of therapeutic glycoproteins.'
Glycosylation is essential to all complex life including plants, animals and fungi.
Cerecor has enrolled its first patient into the CDG FIRST - Congenital Disorders of Glycosylation Formative Retrospective Study - trial, a retrospective study that follows general principles of periodic assessment of CDG patients in routine practice.
Water dispersible polymers are used owing to their high efficiency in the glycosylation reactions.
Among their topics are high-throughput screenings: new breeze in anti-Trypanosoma cruzi drug discovery, protein glycosylation in Trypanosoma cruzi and strategies based on mass spectrometry for characterizing glycans and glycoproteins, omics approaches for understanding gene expression in Leishmania: clues for tackling Leishmaniasis, Entamoeba histolytica: from high-throughput technology to new drugs, and gene silencing and therapeutic targets against Acanthamoeba infections.
(25,42) For several years, it remained unclear whether the mechanism generating these species involved processing, glycosylation, or phosphorylation.
As part of the study, third party researchers analysed the patterns of carbohydrates that attach to the KLH protein through a biologic process known as glycosylation.
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