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(Biology) the state of being gnotobiotic
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌnoʊ toʊ baɪˈoʊ sɪs)

also gno•to•bi•ot•ics

(-ˈɒt ɪks)

the study of organisms or conditions that are free of germs or contaminants or to which a known germ or contaminant has been introduced for purposes of study.
[1945–50; < Greek gnōt(ós) known, v. adj. of gignṓskein to know + -o- + -biosis]
gno`to•bi•ot′ic, adj.
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