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n. (used with a sing. verb)
The study of organisms or environmental conditions that have been rendered free of bacteria or contaminants or into which a known microorganism or contaminant has been introduced for research purposes.

[Greek gnōtos, known; see gnō- in Indo-European roots + biotics, study of living organisms.]

gno′to·bi·ot′ic adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biology) (functioning as singular) the study of organisms living in germ-free conditions or when inoculated with known microorganisms
[C20: from Greek, from gnōtos, from gignōskein to know + bios known life]
ˌgnotobiˈotic adj
ˌgnotobiˈotically adv
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


a branch of biology that studies animals under germ-free conditions.
See also: Biology
-Ologies & -Isms. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Gnotobiotics is a growing field within laboratory animal science.
* 1957 A new field called gnotobiotics, "the study of animals in a germ-free or germ-controlled environment," is described (1/26/57, p.
He presented papers at a number of conferences sponsored by: the National Institutes of Health (1952), the World Health Organization (1954), the American Society for Microbiology (1956, 1967, 1969, 1970, 1972, 1974, 1976-1978, and 1980), the Federation of American Societies for Experimental Biology (1967, 1969, and 1971 - 1979), the American Association of Blood Banks (1967), the 13th International Congress of Blood Transfusions (1972), the 3rd International Congress of Immunology (1977), the U.S.-Japan Intersociety Microbiology Congress (1979), and the Association for Gnotobiotics (1980).