Intensity mucosubstances secreted by goblet cells
along the intestine of Centropomus parallelus and Centropomus undecimalis for each of the histochemical stains used.
In the present study, we show that gestational but not early postnatal exposure of mice to secondhand cigarette smoke (SS) suppresses alveolarization, angiogenesis, and development of Clara and goblet cells
without significant lung inflammation and that the SS-induced effects on alveolar architecture are irreversible.
After TC, eosinophil and neutrophil count decreased and goblet cells
were absent in nasal smear.
To show GIT morphology, and to differentiate between neutral and acidic mucins present within goblet cells
, slides were stained using pH 2.5 Alcian Blue (Sigma Chemicals) and periodic acid-Schiff stain (Sigma Chemicals).
A villiform growth pattern is observed containing goblet cells
with mucous cells, Paneth cells and neuroendocrine cells.
Riccio et al., "Notch/[gamma]-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
," Nature, vol.
To our surprise, we noted that mice lacking TLR4 showed an unusual phenotype that was characterized by a marked increase in goblet cells
The left lung was cut, embedded in paraffin, and sections stained with periodic acid Schiff (PAS) to assess mucous-containing goblet cells
. Sections were viewed using an upright light microscope equipped with SPOT CCD camera and Image Pro software (Olympus Canada, Mississauga, ON).
Cells from the tops of colon crypts showed profiles compatible with mature enterocytes, whereas cell groups from the bottoms of crypts showed profiles compatible with immature cells, goblet cells
, and stem cells/progenitor cells.
These changes include reduction nucleus to cytoplasm ratio, increased epithelial cell sizes, decreased in goblet cells
and the presence of snake-like chromatin.
Histopathological examination showed a cyst wall predominantly lined by ciliated pseudo stratified columnar epithelium with interspersed goblet cells
and partly by stratified squamous epithelium.
The irritation of the airways by the contents of the cigarette smoke causes hypertrophy and hyperplasia of the mucus secreting structures, i.e., the goblet cells
and the submucosal glands.