goitrogenic


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goitrogenic

(ˌɡɔɪtrəˈdʒɛnɪk)
adj
(Pathology) pathol causing goitre
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
Studies of the goitrogenic and tumorigenic effect of two goitrogens in combination with hypophysectomy or thyroid hormone treatment.
Metformin is known to reduce TSH (thyroid stimulating hormone) levels, and this property may be beneficial in refractory hypothyroid patients with concomitant diabetes.8 Older sulfonylureas exhibit a goitrogenic effect, and inhibit the synthesis of thyroid hormone.9 Pioglitazone can cause orbital oedema by increasing IGF1 (insulin like growth factor-1), adipose tissue synthesis and TSH secretion.10 There are reports of increased risk of thyroid malignancy with older sulfonylurea and certain insulin analogues, but these are not substantiated and do not impact modern clinical practice.11,12 Liraglutide is contraindicated in persons with medullary thyroid carcinoma.13
Convenient, quick and power packed meals they are, but gulping down green smoothies everyday with green powders, raw kale and spinach, may not go well with digestion, besides the goitrogenic effect.
Although, there was no clear evidence to fully describe the possible reasons of negative effects of Gls on animal reproduction, it has been reported that Gls led to malnutrition due to thyroid dysfunction, transfer of goitrogenic compounds to fetus and reduced nutrient transfer to fetus through placenta [8].
Other risk factors have been proposed for the coexistence of PTC and PHPT like radiation exposition, the goitrogenic effect of prolonged hypercalcemia, calcitonin elevation, and genetic factors [11, 28].
Cobalt toxicity first became evident following use of cobalt-chloride as a haematopoietic agent in anaemic individuals when it was noted to be goitrogenic [2, 3] and neurotoxic [3].
Studies on patients with acromegaly also demonstrated an enhancement in IGF-1 levels and the rate of multinodular goiter, suggesting a goitrogenic action of IGF-1 [15].
For example, many green, leafy vegetables such as broccoli, kale or bokchoy, contain goitrogenic substances that disrupt the production of thyroid hormones by inhibiting iodine uptake.
Studies on relations between thiocyanate formation and goitrogenic properties of foods.
Must be eaten raw-aldente (Cooking inactivates goitrogenic components)
Other growth factors, as EGF (epithelial growth factor) or IGF1, increased in PHPT, have also a goitrogenic effect [14].