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A noncancerous enlargement of the thyroid gland, visible as a swelling at the front of the neck, that is often associated with iodine deficiency. Also called struma.

[French goitre, back-formation from Old French goitron, throat, gullet, from Vulgar Latin *guttūriō, guttūriōn-, from Latin guttur.]

goi′trous (-trəs) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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References in periodicals archive ?
Hashimoto's thyroiditis: countrywide screening of goitrous healthy young girls in post-iodization phase in India.
Ventriculocordectomy, a new operation for the cure of goitrous glottic stenosis.
Favre, "Prenatal diagnosis of fetal goitrous hypothyroidism in a euthyroid mother: a management challenge," Journal of Ultrasound in Medicine, vol.
It is well-known that HT can coexist with other lesions such as follicular neoplasm, Hurthle cell neoplasm, papillary carcinoma, and goitrous nodules [12-15].
Thyroid status and the levels of thyroid auto-antibodies in the sera of hyperthyroid and goitrous subjects.
In general population, there is an estimated 4-7 percent prevalence of goitre worldwide whereas the incidence of malignancy is about 10 percent in goitrous thyroid2.
Antibodies producing complement-mediated thyroid cytotoxicity in patients with atrophic or goitrous autoimmune thyroiditis.
Bottazzo, "Susceptibility to thyroid autoimmune disease: molecular analysis of HLA-D region genes identifies new markers for goitrous Hashimoto's thyroiditis," The Journal of Clinical Endocrinology & Metabolism, vol.
After 3 days of acclimatization, the rats were randomly divided into 5 groups: normal, model, Euthyrox, HYDf, and HYDp groups; all rats except those in the normal control group received intragastric administration of PTU at a dosage of 0.01 g/kg daily for 14 days to induce the goitrous model according to previously reports [15] and were given different treatments for 28 days, as shown in Table 2.
However, excluding these goitrous women from analysis slightly reduced the incidences of hypothyroidism (8.8% to 8.7%) as well as hyperthyroidism (7.3% to 6.2%) but statistical difference remained comparable (p > 0.05) between female and male HCV positive counterparts.
Breast-milk iodine concentrations (BMIC) are determined by the maternal iodine intake; population medians have been shown to range from 9-32 [micro]g/L in iodine deficient goitrous areas to 146 [micro]g/L in iodine sufficient Chinese women (15,16).
The described histologic features noted "abundant droplets of lipoids" and that "Lubarash's glycogen reaction was positive." The author suggested that these lesions more likely represented "metastases of a hypernephroma" (ie, renal cell carcinoma clear cell type) than a degenerative goitrous process.