Although several reports suggest that spayed and/or neutered dogs have higher incidence of certain cancers, including osteosarcoma, the relationship between reproductive status and cancer risk may be confounded by other variables, such as the documented tendency toward increased adiposity and body condition in gonadectomized
Mice were allocated into three groups (n = 10) for each sex: (1) intact mice (n = 10), (2) bilaterally gonadectomized
(GX) (n = 10) mice, and (3) mice that underwent surgery without gonadectomy (sham operated) (n = 10).
For testosterone deficiency, the rats anesthetized with chloral-hydrate (300 mg/kg) were gonadectomized
(GDX) by the removal of the testes, epididymis, and epididymal fat under aseptic conditions, and the incisions were closed using surgical staples.
Specific suppression of follicle-stimulating hormone secretion in gonadectomized
male and female rats with intrasplenic ovarian transplants.
mice, estrogen replacement has been shown to increase trabecular BMD (3).
However, little is known about these relationships in the coronary vascular bed of gonadectomized
rats or the interaction between estrogens and potassium channels in that group of animals.
A photoperiodic response in gonadectomized
Japanese quail exposed to a single long day.
In rodents, PM extract has been demonstrated to prevent bone loss in both male and female gonadectomized
rats (Urasopon et al.
Bellamy et al (1976, (1)), in his study of rat thymus observed that the maximum weights of thymus attained in gonadectomized
animals were found to be independent of the age at which the animals were gonadectomized
or of the sex of the animal.
sexed, and gonadectomized
. A subsample of ten eggs was obtained from each of 60 females with ripe ovaries.
Ethanol-induced increases in neuroactive steroids in the rat brain and plasma are absent in adrenalectomized and gonadectomized