Doctors and patients alike hailed diethylstilbestrol ("DES") as a "miracle drug." (2) Created by a British scientist in 1938, (3) the Food and Drug Administration ("FDA") approved it three years later "to treat four conditions: menopausal disorders, gonorrheal
vaginitis, senile vaginitis, and unwanted lactation." (4) DES is a synthetic form of estrogen, (5) easier to administer and cheaper to produce than natural estrogen.
Zoliflodacin cured all rectal gonorrheal
infections as did ceftriaxone.
found relatively high prevalence per 100 population of 2.1% among men and 2.6% among women aged 20-64 years for genital chlamydial infection, and chlamydial infection is much more common than gonorrheal
infection in the general population. The prevalence of chlamydial infection among sex workers is 32%. Genital C.
Moreover, the possibility of an infection causing chronic inflammation and leading to OM is very likely in our patient since a purulent cervical discharge is characteristic of gonorrheal
and chlamydial cervicitis .
Women with purulent cervicitis or a current chlamydial or gonorrheal
infection should delay IUD insertion until after treatment.
When it is not caused by a gonorrheal
infection it is known as non-gonococcal urethritis or NGU.
In heterosexuals, the primary sites of gonorrheal
infection are the urethra in men and cervix in women (4).
We presumed the baby had gonorrheal
conjunctivitis; however, serogroup Y, N.
(5) Pelvic Inflammatory Disease (PID) including tuberculosis, chlamydial and gonorrheal
infections are more common predisposing factor in developing countries like ours.
Later, he and a German chemist developed Argyrol, an antiseptic that prevented newborn infants from getting gonorrheal
Since the 1940s, when sulfonamides and penicillin were first used to treat gonorrheal
infections, the bacteria has reliably developed resistance to all antibiotics used against it, including those two original drugs and several more recently developed ones (fluoroquinolones, tetracycline and oral cephalosporins).
The East Indian sandalwood tree, Santalum album L., finds numerous mentions in traditional medicinal systems such as Ayurveda, as antiseptic, antipyretic, antiscabietic, diuretic, expectorant, stimulant, and for the treatment of bronchitis, dysuria, urinary infection, and in gonorrheal
recovery (Dikshit and Hussain 1984).