Also found in: Medical, Wikipedia.


A synthetic peptide analog of gonadotropin-releasing hormone used to treat prostate cancer, endometriosis, and advanced breast cancer.

[Blend of gonadorelin (from gonado(tropin-)rel(easing hormone) + -in) and serine.]


n goserelina
References in periodicals archive ?
However, Gonadotrophin releasing hormone agonist called goserelin has shown satisfactory results in pelvic congestion syndrome treatment pain.
supply of medicinal products, Cancer drugs and pregabalin for the needs of cozl " part 1 - drugs for the operating theater part 2 - ganciclovir part 3 - goserelin part 4 - antiemetics part 5 - omeprazole part 6 - antiemetics part 7 - pcc prothrombin complex concentrate part 8 - antibiotics part 9 - ampoules part 10 - antiemetics part 11 - low molecular weight heparins part 12 - infusion fluids part 12 - infusion fluids part 13 - anidulafungin part 14 - drugs for the operating theater part 15 - antibiotics part 16 - ampoule medicines part 17 - low molecular weight heparins part 18 - pazopanib part 19 - ipilimumabum part 20 - panitumumab part 21 - pregabalin
In MONALEESA-7, Kisqali plus an aromatase inhibitor and goserelin nearly doubled the median PFS compared to an aromatase inhibitor and goserelin alone in pre- or perimenopausal women.
Gonadotropin-releasing hormone (GnRH) analogues, including both GnRH agonists (nafarelin, leuprolide, and goserelin) and GnRH antagonists (elagolix) reduce pelvic pain caused by endometriosis by suppressing pituitary secretion of LH and FSH, thereby reducing ovarian synthesis of estradiol.
In a large randomised multicentre study for the treatment of mastalgia, goserelin (LHRH analog) has shown effect as short-term treatment.
LHRH analogs include; leuprolide (Lupron, Eligard), goserelin (Zoladex), triptorelin (Trelstar), and histrelin (Vantas).
Ovarian ablation versus goserelin with or without tamoxifen in pre-perimenopausal patients with advanced breast cancer: results of a multicentric Italian study.
For such patients, ovarian function must be ablated either with surgery or with gonadotropin-releasing hormone (GnRH) analogues such as leuprorelin and goserelin if aromatase inhibitors are desired.
Prevention of Menopause Induced by Chemotherapy (PROMISE) (21) isimli randomize kontrollu calismada kemoterapi sirasinda Triptorelin ve Goserelin kullaniminin ovaryan yetmezlik gelisimini anlamli sekilde azalttigi gozlenmistir (21).
She said gonadotropin-releasing hormone agonises, such as Zoladex (Goserelin) will cause the estrogen and progesterone levels to drop.
Single-centre Bicalutamide 50 mg daily 153 during the first 4 weeks L, LA, & met Kawakami LHRH(a) (goserelin, leuprolide, 2013 (11) or buserelin) Single-centre 69 Met Dason 2013 (10) LHRH(a) (goserelin, leuprolide, Cohort series or triptorelin), 3-month depots 32 and a 1-month course of L, LA, & met bicalutamide on ADT initiation OR LHRH antagonist (degarelix), 1-month depots Study type/n/ T level setting Klotz [less than or equal to]0.7 nmol/l 2015 (8) RCT, (NT year 1; Multicentre n=489) 626 >0.7 to <1.7 Recurrent nmol/l (NT year 1; n=129) [greater than or equal to]1.7 nmol/l (NT year 1; n=8) Wang 2016 (12) [less than or equal to]0.9 nmol/l Single-centre (n=98) 206 Met >0.9 nmol/l (n=108) Bertaglia <0.7 nmol/l 2013 (9) (n=25)vs.
Cyclic therapy (Gn-RH agonist, leuprolide acetate 1.88 mg, or goserelin acetate 1.8 mg via subcutaneous injection six times every 4 weeks for 24 weeks; DNG, 2 mg/day, oral administration 24-108 weeks) was continued alternately for approximately eight years as endometriosis treatment.