gramicidin


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Related to gramicidin: framycetin

gram·i·ci·din

 (grăm′ĭ-sīd′n)
n.
An antibiotic substance consisting of a mixture of several closely related polypeptides, produced by the soil bacterium Bacillus brevis and used topically to treat infections caused by certain gram-positive bacteria.

gramicidin

(ˌɡræmɪˈsaɪdɪn) or

gramicidin D

n
(Pharmacology) an antibiotic used in treating local Gram-positive bacterial infections: obtained from the soil bacterium Bacillus brevis
[C20: from Gram(-positive) + -cid(e) + -in]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.gramicidin - an antibiotic produced by a soil bacterium; used chiefly as an antiseptic in treating local infections produced by Gram-positive bacteria
antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"
antiseptic - a substance that destroys micro-organisms that carry disease without harming body tissues
Translations

gram·i·ci·din

n. gramicidina, antibiótico producido por Bacillus brevis, localmente activo contra bacterias gram-positivas.

gramicidin

n gramicidina
References in periodicals archive ?
This was the case with Gregory Gause and his discovery of the antibiotic Gramicidin S.
This damaged in bacterial cells was caused by the antimicrobial peptides gramicidin S caused formation of blebs on membrane lead to membrane lysis and cytoplasmic contents were released out the cell.3.7.2.
As shown in Excel Table S1, pinacyanol chloride was the most potent active compound, based on having the lowest [IC.sub.50] values in one of the two assays, with [IC.sub.50] of 0.04 and 0.02 [micro]M in rat primary hepatocytes and HepG2 cells, respectively, followed by chlorfenapyr (0.07 [micro]M in rat hepatocytes, 0.04 [micro]M in HepG2 cells), gramicidin (0.2 [micro]M in rat hepatocytes, 0.04 [micro]M in HepG2 cells), triclocarban (0.17 [micro]M in rat hepatocytes, 0.17 [micro]M in HepG2 cells), 2,6-di-tert-butyl-4-nitrophenol (0.29 [micro]M in rat hepatocytes, 0.11 [micro]M in HepG2 cells), niclosamide (0.44 [micro]M in rat hepatocytes, 0.10 [micro]M in HepG2 cells), and fluorosalan (0.42 [micro]M in rat hepatocytes, 0.19 [micro]M in HepG2 cells).
Betsumiya et al., "Association of tannins and related polyphenols with the cyclic peptide gramicidin S," Chemical & Pharmaceutical Bulletin, vol.
Chen, "The antimicrobial activity of gramicidin a is associated with hydroxyl radical formation," PLoS ONE, vol.
Kriegstein, "Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging," The Journal of Neuroscience: The Official Journal of the Society for Neuroscience, vol.
The novel isolate Paludifilum halophilum strain SMBg3 with significant antimicrobial activity was characterized further and shown to be potential producer of Gramicidin S and four cyclic antimicrobial dipeptides.
Gramicidin S biosynthesis operon containing the structural genes grsA and grsB has an open reading frame encoding a protein homologous to fatty acid thioesterases.