granulocyte colony-stimulating factor


Also found in: Thesaurus, Medical, Legal, Financial, Encyclopedia, Wikipedia.
Related to granulocyte colony-stimulating factor: GCFS, rhG-CSF

granulocyte colony-stimulating factor

n. Abbr. G-CSF
1. A cytokine secreted by a variety of cell types that stimulates progenitor cells in the bone marrow to produce granulocytes, especially neutrophils.
2. A recombinant form of this cytokine, such as the drug filgrastim.
References in periodicals archive ?
A possible mechanism of increase in serum alkaline phosphatase activity in rats given granulocyte colony-stimulating factor. Exp Anim 1996;45:23-32.
Their stem cells were harvested after mobilization with high doses of cyclophosphamide and granulocyte colony-stimulating factor (G-CSF).
It's often preventable with prophylactic administration of granulocyte colony-stimulating factor (G-CSF).
The current management strategy calls for a multimodality approach, including aggressive surgical debridement and the use of antifungal agents for all, and treatment with granulocyte colony-stimulating factor for selected patients.
BioLineRx announced results from the lead-in period of the GENESIS trial, a double-blind, placebo-controlled Phase 3 trial comparing BL-8040 in combination with granulocyte colony-stimulating factor, to G-CSF alone, for the mobilization of hematopoietic stem cells used for autologous transplantation in multiple myeloma patients.
Baby developed severe neutropenia at DOL 2, with absolute polymorphonuclear count <500 [micro]/L, and was started with granulocyte colony-stimulating factor. Due to favorable clinical evolution in addition to negative blood culture, Ampicillin-Gentamicin were discontinued at DOL 5.
It is assumed that about 20% of cases are related to autoimmune disorders and about 40-50% of cases are unexplained RM G-CSF (Granulocyte Colony-stimulating Factor) is a glycoprotein that is secreted from endothelial cells, macrophages and some other immune system cells (6).
Granulocyte colony-stimulating factor (G-CSF) is the most commonly reported inciting drug; however, an extensive list of potential offenders has been described in the literature.
Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the blood.
The stem cell graft contained notable increases in lymphocytes and plasmacytoid dendritic cells compared to administration of G-CSF (granulocyte colony-stimulating factor) and is consistent with preclinical data suggesting a possible better outcome for recipients.
Granulocyte colony-stimulating factor (G-CSF) is a member of the cytokine family of growth factors.

Full browser ?