References in periodicals archive
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During a period of three years, beginning April 2009, Shire will transition several products, including Carbatrol (carbamezepine), Intuniv (guanfacine extended release), Lialda (mesalamine), Pentasa (mesalamine) and Vyvanse (lisdexamfetamine dimesylate) from its Owings Mills, MD facility to DSM's facility in Greenville, NC.
(9-11) There are a number of pharmacological treatment options based on the effects of the release/inhibition of neurotransmitters, including stimulants (methylphenidate, amphetamine, modafinil, pemoline), selective norepinephrine/serotonin reuptake inhibitors (atomoxetine), antidepressants (bupropion, desipramine), nicotinic agents (nicotine analogs), and antihypertensives (clonidine, guanfacine).
The results indicated that the potency (pEC50 values) rank order was Dexmedetomidine > Guanabenz > p-aminoclonidine > UK-14304 > Oxymetazoline > Clonidine > Xylometazoline > Guanfacine > Naphazoline > (-)EPI > [alpha]-methyl-NE > 6-FNE > (-)NE > Deoxy EPI > Dopamine (deoxyNE) > Xylazine > (+)-NE > (-)-Phenylephrine > Isoproterenol.
So do some hypertensives like Clonidine, guanfacine, and alpha-methyldopa.
(51) reported on 80 children with PDDs who were treated with guanfacine in open label fashion.
Anti-inflammatory actions of clonidine, guanfacine and B-HT 920 against various inflammagen-induced acute paw oedema in rats.
A placebo controlled study of guanfacine in the treatment of children with tic disorders and attention deficit hyperactivity disorder.
In the past four years he has seen sixteen physicians, who have prescribed over nineteen medications--ritalin, dexedrine, adderall, depakote, imipramine, clonidine, thioridazine, guanfacine, tegretol, and others.
These agents are among the oldest indicated for the treatment of hypertension and include clonidine (Catapres[R]), guanabenz (Wytensin[R]), guanfacine (Tenex[R]), and methyldopa (Aldomet[R]), all of which are available generically.
Note, however, that three sudden deaths occurred with this same combination and that an alternative is to switch Dexedrine with Ritalin and guanfacine (another alpha 2 agonist) with clonidine (Dulcan, Dunne, et al., 1997).
(Commonly used nervous system inhibitors include clonidine, guanfacine, methyldopa.)
doxazosin mesylate (Cardura) guanfacine HCI (Tenex) hydralazine HCI (Apresoline) labetalol HCI (Normodyne, Trandate) metoprolol tartrate (Lopressor, Toprol XL) nadolol (Corgard) prazosin HCI (Minipress) terazosin HCI (Hytrin) valsartan (Diovan) Psychotherapeutic medications amitriptyline HCI (Elavil) Treats depression.
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