Massive oxidative haemolysis
and renal failure caused by high dose vitamin C.
The recommended indication is for the treatment of adult patients with paroxysmal nocturnal haemoglobinuria (PNH) with haemolysis
with clinical symptoms indicative of high disease activity,1 and also for adult patients who are clinically stable2 after having been treated with SOLIRIS[R] (eculizumab) for at least the past six months.
The recommended indication is for the treatment of adult patients with paroxysmal nocturnal haemoglobinuria with haemolysis
with clinical symptoms indicative of high disease activity, and also for adult patients who are clinically stable after having been treated with Soliris (eculizumab) for at least the past six months.
: an overview of the leading cause of unsuitable specimens in clinical laboratories.
rhabdomyolysis or haemolysis
), and decreased excretion (e.g.
However, aspirating blood from a PIVC is not a therapeutic indication for a PIVC and this collection route increases haemolysis
and blood specimen rejection when compared to direct venepuncture.
Keywords: Glucose-6-phosphate dehydrogenase, G6PD, Hepatitis E, Haemolysis
Haemolysin production was detected by presence of a zone of complete haemolysis
around the inoculation site (Raksha et al, 2003; EL-Mosallamy et al, 2015; Tabasi et al., 2015).
Also, as the study was retrospective, the confounding effect of some other factors, such as polycythaemia, haemoglobinopathies, or blood sample haemolysis
, could not be assessed.
From the finding of present study, it could be ascertained that in group B and C haemolysis
continued even after treatment for Babesiosis along with single drug indicating improper response to therapy (Susan et al., 2001) and resulted continuation of haemolysis
and production of direct serum bilirubin values, while direct serum bilirubin values in group D, E and F decreased from respective therapies (Vial and Gorenflot, 2006).
[7, 8] Jaundice in falciparum malaria is due to intravascular haemolysis
of parasitized RBCs, hepatic dysfunction and microangiopathic haemolysis
due to DIC.
In fast-moving blood, it can lead to haemolysis
: red blood cells rupturing.