hairy cell leukemia


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Related to hairy cell leukemia: Cladribine

hairy cell leukemia

also hair·y-cell leukemia  (hâr′ē-sĕl′)
n.
A rare, chronic form of leukemia characterized by accumulation in the bone marrow, spleen, and liver of B cells that have numerous hairlike surface projections.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
The "Global Hairy Cell Leukemia Therapeutics Market 2019-2023" report has been added to ResearchAndMarkets.com's offering.
Public healthcare company The US Food and Drug Administration Thursday authorised the marketing of Lumoxiti (moxetumomab pasudotox-tdfk) injection for intravenous use for the treatment of adult patients with relapsed or refractory hairy cell leukemia (HCL).
Because of metastatic MCC and associated poor prognosis, it was decided not to commence the treatment for hairy cell leukemia.
(57) Hairy cell leukemia is positive for all common B-cell antigens (CD19, CD20, CD79a, FMC-7, and PAX5), with characteristic expression of annexin A1 (Figure 7, A), CD11c, CD25, CD103, CD123, DBA-44 (CD72) (Figure 7, B), the Hector Battifora mesothelial epitope-1 (HBME-1), pERK, Tbet, and TRAP58-61 but is typically negative for CD5 and CD10, although 10% to 20% of HCLs are positive for CD10.
GlobalData's clinical trial report, "Hairy Cell Leukemia Global Clinical Trials Review, H1, 2016" provides an overview of Hairy Cell Leukemia clinical trials scenario.
Likewise, in the same study there were some limited associations with diffuse large B-cell lymphoma, hairy cell leukemia, splenic B-cell marginal zone lymphoma, and Waldenstrom macroglobulinemia.
[USPRwire, Fri Aug 07 2015] Global Markets Direct's, 'Hairy Cell Leukemia - Pipeline Review, H1 2015', provides an overview of the Hairy Cell Leukemia's therapeutic pipeline.
(14) Others report a worse prognosis especially in patients with plasmacytic and Hairy cell leukemia. (6)
Differential diagnosis include B-cell chronic lymphocytic leukemia, hairy cell leukemia and marginal zonelymphomas with circulating lymphocytes.
For the last 30 years, cladribine has been used in the treatment of hairy cell leukemia (HCL)--with good results in most cases.
A form of reactive mast cell hyperplasia, which is observed in other hematologic neoplasms, such as lymphoplasmacytic lymphoma and hairy cell leukemia (HCL) must be excluded [3].