Also found in: Medical, Encyclopedia, Wikipedia.


 (hăp′tĕn′) also hap·tene (-tēn′)
A small molecule that reacts with a specific antibody but does not induce an immune response unless bound to a larger molecule, usually a protein.

[German : Greek haptein, to fasten + German -en, noun suffix (from Greek -ēnē, -ene).]

hap·ten′ic adj.


(Physiology) immunol relating to a hapten
References in periodicals archive ?
Examples of such reactive, haptenic compounds that frequently lead to sensitization after dermal contact or inhalation are toluene diisocyanate, trimellitic anhydride, phthalic anhydride, benzoquinone, formaldehyde, ethylene oxide, dinitrochlorobenzene, picryl chloride, penicillins, and D-penicillinamine.
The cause may be due to environmental factors such as bacterial or viral infections, or haptenic toxic chemicals binding to human tissue, causing modification of self-antigens and the subsequent production of autoantibodies.
Synthesis of 2,3-di-Omethyl4-O-(3,6,-di-O-methyl-b-D-glycopyranosyl)-L-rhamnopyranose (and its a-propyl glycoside)-a haptenic portion of the major glycolipid from Mycobacterium leprae.