haptoglobin


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hap·to·glo·bin

 (hăp′tə-glō′bĭn)
n.
A plasma protein that is a normal constituent of blood serum and functions in the binding of free hemoglobin in the bloodstream.

[Greek haptein, to bind, fasten + (hemo)globin.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

haptoglobin

(ˌhæptəˈɡləʊbɪn)
n
1. (Biochemistry)
a. a protein that is present in blood plasma and can join with free haemoglobin
b. (as modifier): haptoglobin genes.
2. (Biochemistry) (as modifier): haptoglobin genes.
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.haptoglobin - a protein in plasma that binds free hemoglobin and removes it (as from wounds)
protein - any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

hap·to·glo·bin

[MIM*140100 & 140210]
n. haptoglobina, mucoproteína que se une a la hemoglobina libre en el plasma.
English-Spanish Medical Dictionary © Farlex 2012
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References in periodicals archive ?
The stroke rate in women with the 2-1 haptoglobin genotype was 5.7% in those who received vitamin E and 1.2% in the placebo arm, a 4.5-fold increased rate of stroke after adjustment, said Dr.
Release of inflammatory cytokines initiates the production of spectrum of acute phase proteins (such as C-reactive protein, haptoglobin, transferrin etc) by the liver cells.
AIMS: Individuals with both diabetes mellitus (DM) and the Haptoglobin (Hp) 2-2 genotype are at increased risk of cardiovascular disease.
In these animals, haptoglobin (Hp) and serum amyloid A (SAA) are the major APPs, and have a great potential to be used as diagnostic indicators in metabolic problems (18).
Haptoglobin was less than 8 mg/dL, and electrolytes were markedly abnormal, with a sodium level of 123 mg/dL, potassium 4.8 mmol/L, chloride 93 mmol/L, carbon dioxide 18 mmol/L, blood urea nitrogen (BUN) 28 mg/dL, creatinine 3.3 mg/dL, and calcium 13.68 mg/dL.
Volunteers who drank sugar-sweetened beverages have also been shown to have increases in the inflammatory markers haptoglobin, transferrin, and C-reactive protein, whereas aspartame-sweetened beverage drinkers had large declines in the same markers.
Typical laboratory features common to all forms of extravascular hemolysis include indirect hyperbilirubinemia and increased concentration of lactate dehydrogenase, whereas the hallmarks of intravascular hemolysis include a decrease in the serum level of haptoglobin and an increase in plasma-free hemoglobin [14].
They also had markedly altered protein components of HDL, including elevated levels of haptoglobin, hemoglobin, apo A-1, myeloperoxidase, and hemopexin (in plasma but not in HDL) and lower lecithin cholesterol acyltransferase (LCAT).
Transferrin concentration decreased after the 2000-m race (-0.60 [+ or -] 0.25, p < 0.05), and concentration changes of haptoglobin differed between [NAT.sub.2000] (tendency to be reduced) and COL (tendency to by enhanced) (p < 0.05).
Intravascular hemolysis is diagnosed with laboratory studies that show anemia, low haptoglobin, elevated lactate dehydrogenase, and blood smear schistocytes.
On the basis of plasmatic Hb, the proportion of hemolysis and haptoglobin consumed, taking in account the variation of plasma haptoglobin and intravascular hemolysis after and at least three hours post-exercise, were calculated.